Cognitive impairment and factors influencing depression in adolescents with suicidal and self-injury behaviors: a cross-sectional study
Abstract Background Non-suicidal self-injury (NSSI) and suicide attempts (SAs) by adolescent patients with depression have become serious public health problems. There is still insufficient research evidence on the effects of NSSI and SAs on neurocognitive functioning in adolescents. Cognitive funct...
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| Format: | Article |
| Language: | English |
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BMC
2023-04-01
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| Series: | BMC Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12888-023-04726-8 |
| _version_ | 1827966167056121856 |
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| author | Hong Chen Lan Hong Siyu Tong Mengjia Li Shiyu Sun Yao Xu Jie Liu Tianqi Feng Yuting Li Guangyao Lin Fanfan Lu Qiaole Cai Dongwu Xu Ke Zhao Tiansheng Zheng |
| author_facet | Hong Chen Lan Hong Siyu Tong Mengjia Li Shiyu Sun Yao Xu Jie Liu Tianqi Feng Yuting Li Guangyao Lin Fanfan Lu Qiaole Cai Dongwu Xu Ke Zhao Tiansheng Zheng |
| author_sort | Hong Chen |
| collection | DOAJ |
| description | Abstract Background Non-suicidal self-injury (NSSI) and suicide attempts (SAs) by adolescent patients with depression have become serious public health problems. There is still insufficient research evidence on the effects of NSSI and SAs on neurocognitive functioning in adolescents. Cognitive function alterations may be associated with SAs and self-injury. NSSI and SAs have different influencing factors. Methods Participants were recruited from outpatient clinics and included 142 adolescent patients with depression (12–18 years old). This cohort included the SAs group (n = 52), NSSI group (n = 65), and depression without SAs/NSSI control group (n = 25). All participants underwent a clinical interview and neuropsychological assessment for group comparisons, and post-hoc tests were performed. Finally, partial correlation analysis was used to explore factors related to changes in cognitive function. Results The SAs group performed significantly worse than the control group in executive function and working memory. The depression score was directly proportional to the executive function of the SAs group, whereas cognitive functioning in the NSSI group was associated with borderline traits and rumination. Conclusions These findings suggest that impairment of executive function and working memory may be a common pattern in adolescent depressed patients with SAs. However, borderline traits and rumination may be indicative of NSSI but not SAs. |
| first_indexed | 2024-04-09T17:45:43Z |
| format | Article |
| id | doaj.art-1b815c4b43dc44e58153f1928edaa1b2 |
| institution | Directory Open Access Journal |
| issn | 1471-244X |
| language | English |
| last_indexed | 2024-04-09T17:45:43Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj.art-1b815c4b43dc44e58153f1928edaa1b22023-04-16T11:21:21ZengBMCBMC Psychiatry1471-244X2023-04-0123111110.1186/s12888-023-04726-8Cognitive impairment and factors influencing depression in adolescents with suicidal and self-injury behaviors: a cross-sectional studyHong Chen0Lan Hong1Siyu Tong2Mengjia Li3Shiyu Sun4Yao Xu5Jie Liu6Tianqi Feng7Yuting Li8Guangyao Lin9Fanfan Lu10Qiaole Cai11Dongwu Xu12Ke Zhao13Tiansheng Zheng14Department of Psychiatry, First Affiliated Hospital of Wenzhou Medical UniversityThe Third Hospital of QuZhouSchool of Mental Health, Wenzhou Medical UniversitySchool of Mental Health, Wenzhou Medical UniversitySchool of Mental Health, Wenzhou Medical UniversitySchool of Mental Health, Wenzhou Medical UniversitySchool of Mental Health, Wenzhou Medical UniversitySchool of Mental Health, Wenzhou Medical UniversitySchool of Mental Health, Wenzhou Medical UniversityThe Affiliated Kangning Hospital of Wenzhou Medical University Zhejiang Provincial Clinical Research Center for Mental DisorderThe Affiliated Kangning Hospital of Wenzhou Medical University Zhejiang Provincial Clinical Research Center for Mental DisorderThe Affiliated Kangning Hospital of Wenzhou Medical University Zhejiang Provincial Clinical Research Center for Mental DisorderSchool of Mental Health, Wenzhou Medical UniversityLishui Second People’s Hospital Afliated to Wenzhou Medical UniversityThe Affiliated Kangning Hospital of Wenzhou Medical University Zhejiang Provincial Clinical Research Center for Mental DisorderAbstract Background Non-suicidal self-injury (NSSI) and suicide attempts (SAs) by adolescent patients with depression have become serious public health problems. There is still insufficient research evidence on the effects of NSSI and SAs on neurocognitive functioning in adolescents. Cognitive function alterations may be associated with SAs and self-injury. NSSI and SAs have different influencing factors. Methods Participants were recruited from outpatient clinics and included 142 adolescent patients with depression (12–18 years old). This cohort included the SAs group (n = 52), NSSI group (n = 65), and depression without SAs/NSSI control group (n = 25). All participants underwent a clinical interview and neuropsychological assessment for group comparisons, and post-hoc tests were performed. Finally, partial correlation analysis was used to explore factors related to changes in cognitive function. Results The SAs group performed significantly worse than the control group in executive function and working memory. The depression score was directly proportional to the executive function of the SAs group, whereas cognitive functioning in the NSSI group was associated with borderline traits and rumination. Conclusions These findings suggest that impairment of executive function and working memory may be a common pattern in adolescent depressed patients with SAs. However, borderline traits and rumination may be indicative of NSSI but not SAs.https://doi.org/10.1186/s12888-023-04726-8Neurocognitive functionAdolescentsDepressionNSSISuicide attempts |
| spellingShingle | Hong Chen Lan Hong Siyu Tong Mengjia Li Shiyu Sun Yao Xu Jie Liu Tianqi Feng Yuting Li Guangyao Lin Fanfan Lu Qiaole Cai Dongwu Xu Ke Zhao Tiansheng Zheng Cognitive impairment and factors influencing depression in adolescents with suicidal and self-injury behaviors: a cross-sectional study BMC Psychiatry Neurocognitive function Adolescents Depression NSSI Suicide attempts |
| title | Cognitive impairment and factors influencing depression in adolescents with suicidal and self-injury behaviors: a cross-sectional study |
| title_full | Cognitive impairment and factors influencing depression in adolescents with suicidal and self-injury behaviors: a cross-sectional study |
| title_fullStr | Cognitive impairment and factors influencing depression in adolescents with suicidal and self-injury behaviors: a cross-sectional study |
| title_full_unstemmed | Cognitive impairment and factors influencing depression in adolescents with suicidal and self-injury behaviors: a cross-sectional study |
| title_short | Cognitive impairment and factors influencing depression in adolescents with suicidal and self-injury behaviors: a cross-sectional study |
| title_sort | cognitive impairment and factors influencing depression in adolescents with suicidal and self injury behaviors a cross sectional study |
| topic | Neurocognitive function Adolescents Depression NSSI Suicide attempts |
| url | https://doi.org/10.1186/s12888-023-04726-8 |
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