Harnessing Protein-Ligand Interaction Fingerprints to Predict New Scaffolds of RIPK1 Inhibitors

Harnessing Protein-Ligand Interaction Fingerprints to Predict New Scaffolds of RIPK1 Inhibitors

Necroptosis has emerged as an exciting target in oncological, inflammatory, neurodegenerative, and autoimmune diseases, in addition to acute ischemic injuries. It is known to play a role in innate immune response, as well as in antiviral cellular response. Here we devised a concerted in silico and e...

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Bibliografske podrobnosti
Main Authors: Natália Aniceto, Vanda Marques, Joana D. Amaral, Patrícia A. Serra, Rui Moreira, Cecília M. P. Rodrigues, Rita C. Guedes
Format: Article
Jezik:English
Izdano: MDPI AG 2022-07-01
Serija:Molecules
Teme:
necroptosis
RIPK1
inhibitors
docking
machine learning
QSAR
Online dostop:https://www.mdpi.com/1420-3049/27/15/4718

Internet

https://www.mdpi.com/1420-3049/27/15/4718

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