A Report of Multiple Sclerosis Registry in Mazandaran Province 2019-2021
Background and purpose: Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system. The purpose of this study was to report the information of MS patients registered in Mazandaran MS Registry System between 2019 and 2021. Materials and methods: This...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2022-04-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
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| Online Access: | http://jmums.mazums.ac.ir/article-1-17169-en.html |
| _version_ | 1797893410607071232 |
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| author | Seyed Mohammad Baghbanian Abolfazl Hosseinnataj Sharaeh Eskandarieh Mohammadali Sahraian |
| author_facet | Seyed Mohammad Baghbanian Abolfazl Hosseinnataj Sharaeh Eskandarieh Mohammadali Sahraian |
| author_sort | Seyed Mohammad Baghbanian |
| collection | DOAJ |
| description | Background and purpose: Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system. The purpose of this study was to report the information of MS patients registered in Mazandaran MS Registry System between 2019 and 2021.
Materials and methods: This retrospective study was performed in patients with MS living in Mazandaran province using the MS national registry system in Iran.
Results: A total of 2211 patients were found, including 72.8% females and the mean age of patients was 36.97±9.47 years. Most of the patients had Relapsing remitting (RR) MS (61.2%) followed by Secondary progressive (SP) MS (19.6%) and a family history of the disease was seen in 16.2%. Most of the patients lived in populated cities; Sari and Amol. Interferons, Rituximab, and Fingolimod were found to be the most widely used drugs. The mean score for Expanded Disability Status Scale (EDSS) was higher in men than women. The mean EDSS scores were the lowest in clinically isolated syndrome (CIS) type of the disease and the highest in the SP and RP types. The level of disability was significantly higher in men than women (P<0.001).
Conclusion: The types of MS in Mazandaran province is similar to global data of this disease, but the increasing prevalence of familial MS in this province compared with other provinces requires more detailed studies. |
| first_indexed | 2024-04-10T06:52:29Z |
| format | Article |
| id | doaj.art-1b87ea391cc7478e9ad0e91e6f0ae4ab |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T06:52:29Z |
| publishDate | 2022-04-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-1b87ea391cc7478e9ad0e91e6f0ae4ab2023-02-28T08:02:53ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792022-04-013220795101A Report of Multiple Sclerosis Registry in Mazandaran Province 2019-2021Seyed Mohammad Baghbanian0Abolfazl Hosseinnataj1Sharaeh Eskandarieh2Mohammadali Sahraian3 Associate Professor, Department of Neurology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Assistant Professor, Department of Biostatistics and Epidemiology, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran Associate Professor, Department of Epidemiology, MS Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran Professor, Department of Neurology, MS Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran Background and purpose: Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system. The purpose of this study was to report the information of MS patients registered in Mazandaran MS Registry System between 2019 and 2021. Materials and methods: This retrospective study was performed in patients with MS living in Mazandaran province using the MS national registry system in Iran. Results: A total of 2211 patients were found, including 72.8% females and the mean age of patients was 36.97±9.47 years. Most of the patients had Relapsing remitting (RR) MS (61.2%) followed by Secondary progressive (SP) MS (19.6%) and a family history of the disease was seen in 16.2%. Most of the patients lived in populated cities; Sari and Amol. Interferons, Rituximab, and Fingolimod were found to be the most widely used drugs. The mean score for Expanded Disability Status Scale (EDSS) was higher in men than women. The mean EDSS scores were the lowest in clinically isolated syndrome (CIS) type of the disease and the highest in the SP and RP types. The level of disability was significantly higher in men than women (P<0.001). Conclusion: The types of MS in Mazandaran province is similar to global data of this disease, but the increasing prevalence of familial MS in this province compared with other provinces requires more detailed studies.http://jmums.mazums.ac.ir/article-1-17169-en.htmlmultiple sclerosisiran national ms registrymazandaran province |
| spellingShingle | Seyed Mohammad Baghbanian Abolfazl Hosseinnataj Sharaeh Eskandarieh Mohammadali Sahraian A Report of Multiple Sclerosis Registry in Mazandaran Province 2019-2021 Journal of Mazandaran University of Medical Sciences multiple sclerosis iran national ms registry mazandaran province |
| title | A Report of Multiple Sclerosis Registry in Mazandaran
Province 2019-2021 |
| title_full | A Report of Multiple Sclerosis Registry in Mazandaran
Province 2019-2021 |
| title_fullStr | A Report of Multiple Sclerosis Registry in Mazandaran
Province 2019-2021 |
| title_full_unstemmed | A Report of Multiple Sclerosis Registry in Mazandaran
Province 2019-2021 |
| title_short | A Report of Multiple Sclerosis Registry in Mazandaran
Province 2019-2021 |
| title_sort | report of multiple sclerosis registry in mazandaran province 2019 2021 |
| topic | multiple sclerosis iran national ms registry mazandaran province |
| url | http://jmums.mazums.ac.ir/article-1-17169-en.html |
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