Potential quorum-sensing inhibitor of Hafnia alvei H4—theaflavin-3,3´-digallate analyzed by virtual screening and molecular simulation

Potential quorum-sensing inhibitor of Hafnia alvei H4—theaflavin-3,3´-digallate analyzed by virtual screening and molecular simulation

ABSTRACT Hafnia species can cause food spoilage via the quorum-sensing (QS) system. Thus, strategies that target QS in these bacteria might be a good approach to safeguard the quality of processed food. In this study, the amino acid sequence of the LasI Ha protein, a key QS regulator from Hafnia alv...

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Bibliographic Details
Main Authors: Xue Li, Congyang Yan, Yanan Wang, Gongliang Zhang, Jingran Bi, Hongshun Hao, Hongman Hou
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
quorum sensing inhibitor
virtual screening
TF3
Hafnia alvei
molecular docking
molecular dynamics simulation
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02671-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02671-23

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