How Many Fenestrations Should I Make When Placing a Baerveldt Glaucoma Implant? A Laboratory Study
Abstract Purpose: This study investigates the effect of one versus two fenestrations on both fluid egress and opening pressure from a non-valved glaucoma implant. Methods: In this laboratory study, we used an in vitro closed system comprised of ligated silicone tubing connected to a fluid reservoir...
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| Format: | Article |
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Knowledge E
2023-04-01
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| Series: | Journal of Ophthalmic & Vision Research |
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| Online Access: | https://doi.org/10.18502/jovr.v18i2.13181 |
| _version_ | 1797830421408382976 |
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| author | Michael C Yang Christopher D Yang Ken Y Lin |
| author_facet | Michael C Yang Christopher D Yang Ken Y Lin |
| author_sort | Michael C Yang |
| collection | DOAJ |
| description | Abstract Purpose: This study investigates the effect of one versus two fenestrations on both fluid egress and opening pressure from a non-valved glaucoma implant. Methods: In this laboratory study, we used an in vitro closed system comprised of ligated silicone tubing connected to a fluid reservoir and manometer to simulate the tubing found in a Baerveldt glaucoma drainage implant. Fenestrations were created using an 8-0 Vicryl TG140-8 suture needle. Main outcome measures included volume of fluid egress and fenestration opening pressures, which were measured via micropipette and increasing pressure until fluid egress was observed. Results: No significant difference was observed in fluid egress between tubing with one versus two fenestrations at pressures ≤ 40 mmHg. At 50 mmHg, a statistically significant difference was observed in fluid egress between tubing with one versus two fenestrations (P < 0.05). The first fenestration opened at 10.5 ± 3.77 mmHg and the second fenestration opened at 28.83 ± 5.09 mmHg (average ± standard deviation). Conclusion: Our in vitro findings suggest there may exist a critical pressure > 40 mmHg at which the second fenestration starts to play a significant role in fluid drainage. There may be no difference in the amount of fluid egress and effect on intraocular pressure between one or two tube fenestrations when preoperative intraocular pressure is ≤ 40 mmHg. |
| first_indexed | 2024-04-09T13:35:47Z |
| format | Article |
| id | doaj.art-1b8e812769f248baa9e0601722ea8276 |
| institution | Directory Open Access Journal |
| issn | 2008-2010 2008-322X |
| language | English |
| last_indexed | 2024-04-09T13:35:47Z |
| publishDate | 2023-04-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-1b8e812769f248baa9e0601722ea82762023-05-09T08:45:31ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2023-04-0118215716310.18502/jovr.v18i2.13181jovr.v18i2.13181How Many Fenestrations Should I Make When Placing a Baerveldt Glaucoma Implant? A Laboratory StudyMichael C Yang0Christopher D Yang1Ken Y Lin2 Gavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, California Gavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, California Gavin Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, CaliforniaAbstract Purpose: This study investigates the effect of one versus two fenestrations on both fluid egress and opening pressure from a non-valved glaucoma implant. Methods: In this laboratory study, we used an in vitro closed system comprised of ligated silicone tubing connected to a fluid reservoir and manometer to simulate the tubing found in a Baerveldt glaucoma drainage implant. Fenestrations were created using an 8-0 Vicryl TG140-8 suture needle. Main outcome measures included volume of fluid egress and fenestration opening pressures, which were measured via micropipette and increasing pressure until fluid egress was observed. Results: No significant difference was observed in fluid egress between tubing with one versus two fenestrations at pressures ≤ 40 mmHg. At 50 mmHg, a statistically significant difference was observed in fluid egress between tubing with one versus two fenestrations (P < 0.05). The first fenestration opened at 10.5 ± 3.77 mmHg and the second fenestration opened at 28.83 ± 5.09 mmHg (average ± standard deviation). Conclusion: Our in vitro findings suggest there may exist a critical pressure > 40 mmHg at which the second fenestration starts to play a significant role in fluid drainage. There may be no difference in the amount of fluid egress and effect on intraocular pressure between one or two tube fenestrations when preoperative intraocular pressure is ≤ 40 mmHg.https://doi.org/10.18502/jovr.v18i2.13181baerveldtdrainage implantsfenestrationglaucomaopening pressure |
| spellingShingle | Michael C Yang Christopher D Yang Ken Y Lin How Many Fenestrations Should I Make When Placing a Baerveldt Glaucoma Implant? A Laboratory Study Journal of Ophthalmic & Vision Research baerveldt drainage implants fenestration glaucoma opening pressure |
| title | How Many Fenestrations Should I Make When Placing a Baerveldt Glaucoma Implant? A Laboratory Study |
| title_full | How Many Fenestrations Should I Make When Placing a Baerveldt Glaucoma Implant? A Laboratory Study |
| title_fullStr | How Many Fenestrations Should I Make When Placing a Baerveldt Glaucoma Implant? A Laboratory Study |
| title_full_unstemmed | How Many Fenestrations Should I Make When Placing a Baerveldt Glaucoma Implant? A Laboratory Study |
| title_short | How Many Fenestrations Should I Make When Placing a Baerveldt Glaucoma Implant? A Laboratory Study |
| title_sort | how many fenestrations should i make when placing a baerveldt glaucoma implant a laboratory study |
| topic | baerveldt drainage implants fenestration glaucoma opening pressure |
| url | https://doi.org/10.18502/jovr.v18i2.13181 |
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