Effect of retrograde intrarenal surgery on the inflammatory reaction, renal function indicators and clinical efficacy in male patients with kidney stones
To investigate the effect of retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotripsy on the inflammatory reaction, renal function indicators and clinical efficacy in male patients with kidney stones. 122 male patients with kidney stones were separated into the study group (n = 61...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MRE Press
2023-02-01
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| Series: | Journal of Men's Health |
| Subjects: | |
| Online Access: | https://oss.jomh.org/files/article/20230228-45/pdf/JOMH2022122301.pdf |
| _version_ | 1797326561980973056 |
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| author | Bin Qin Weihao Luo Qingguo Wu Peng Yang Yiwen Liang Hanchu Ji Zhaokai Gan |
| author_facet | Bin Qin Weihao Luo Qingguo Wu Peng Yang Yiwen Liang Hanchu Ji Zhaokai Gan |
| author_sort | Bin Qin |
| collection | DOAJ |
| description | To investigate the effect of retrograde
intrarenal surgery (RIRS) and percutaneous nephrolithotripsy on the inflammatory
reaction, renal function indicators and clinical efficacy in male patients with
kidney stones. 122 male patients with kidney stones were separated into the study
group (n = 61) and the control group (n = 61) in terms of distinct clinical
treatment regimens. The study group was treated with retrograde intrarenal
surgery, while the control group was treated with percutaneous nephrolithotripsy.
Inflammatory reaction indicators (Interleukin-6 (IL-6), Interleukin-10 (IL-10),
serum tumor necrosis factor-α (TNF-α)), renal function
indicators (blood urea nitrogen (BUN), serum creatinine (Scr), blood uric acid
(BUA), serum β2 microglobulin (BMG)) and other clinical indicators
(operative time, hospital stay, intraoperative blood loss, Visual analogue scale
(VAS) pain score, complications) were observed and compared. Upon the treatment,
significantly lowered inflammatory factors including IL-6, IL-10, TNF-α
and renal function indicators including BUN, Scr, BUA, BMG were shown in study
group. Notably shortened operative time and hospital stay were presented in study
group with lowered intraoperative blood loss and pain score. The total incidence
of complications in study group was 3.28%, significantly lower than 14.75% in
control group. Compared with percutaneous nephrolithotripsy, retrograde
intrarenal surgery for the treatment of male kidney stones with a diameter of
less than 3 cm can improve the inflammatory reaction of male patients, maximize
the preservation of renal function indicators, and eminently promote the clinical
comprehensive efficacy. |
| first_indexed | 2024-03-08T06:26:01Z |
| format | Article |
| id | doaj.art-1b8fc1f7faf143a3b7b42b49b1759005 |
| institution | Directory Open Access Journal |
| issn | 1875-6859 |
| language | English |
| last_indexed | 2024-03-08T06:26:01Z |
| publishDate | 2023-02-01 |
| publisher | MRE Press |
| record_format | Article |
| series | Journal of Men's Health |
| spelling | doaj.art-1b8fc1f7faf143a3b7b42b49b17590052024-02-03T14:30:17ZengMRE PressJournal of Men's Health1875-68592023-02-01192455010.22514/jomh.2023.017S1875-6867(23)00475-XEffect of retrograde intrarenal surgery on the inflammatory reaction, renal function indicators and clinical efficacy in male patients with kidney stonesBin Qin0Weihao Luo1Qingguo Wu2Peng Yang3Yiwen Liang4Hanchu Ji5Zhaokai Gan6Department of Urology, The Eighth Affiliated Hospital of Guangxi Medical University, The People’s Hospital of Guigang, 537100 Guigang, Guangxi, ChinaDepartment of Urology, The First Affiliated Hospital of Guangxi Medical University, 530022 Nanning, Guangxi, ChinaDepartment of Urology, The Eighth Affiliated Hospital of Guangxi Medical University, The People’s Hospital of Guigang, 537100 Guigang, Guangxi, ChinaDepartment of Urology, The Eighth Affiliated Hospital of Guangxi Medical University, The People’s Hospital of Guigang, 537100 Guigang, Guangxi, ChinaDepartment of Urology, The Eighth Affiliated Hospital of Guangxi Medical University, The People’s Hospital of Guigang, 537100 Guigang, Guangxi, ChinaDepartment of Urology, The Eighth Affiliated Hospital of Guangxi Medical University, The People’s Hospital of Guigang, 537100 Guigang, Guangxi, ChinaDepartment of Urology, The Eighth Affiliated Hospital of Guangxi Medical University, The People’s Hospital of Guigang, 537100 Guigang, Guangxi, ChinaTo investigate the effect of retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotripsy on the inflammatory reaction, renal function indicators and clinical efficacy in male patients with kidney stones. 122 male patients with kidney stones were separated into the study group (n = 61) and the control group (n = 61) in terms of distinct clinical treatment regimens. The study group was treated with retrograde intrarenal surgery, while the control group was treated with percutaneous nephrolithotripsy. Inflammatory reaction indicators (Interleukin-6 (IL-6), Interleukin-10 (IL-10), serum tumor necrosis factor-α (TNF-α)), renal function indicators (blood urea nitrogen (BUN), serum creatinine (Scr), blood uric acid (BUA), serum β2 microglobulin (BMG)) and other clinical indicators (operative time, hospital stay, intraoperative blood loss, Visual analogue scale (VAS) pain score, complications) were observed and compared. Upon the treatment, significantly lowered inflammatory factors including IL-6, IL-10, TNF-α and renal function indicators including BUN, Scr, BUA, BMG were shown in study group. Notably shortened operative time and hospital stay were presented in study group with lowered intraoperative blood loss and pain score. The total incidence of complications in study group was 3.28%, significantly lower than 14.75% in control group. Compared with percutaneous nephrolithotripsy, retrograde intrarenal surgery for the treatment of male kidney stones with a diameter of less than 3 cm can improve the inflammatory reaction of male patients, maximize the preservation of renal function indicators, and eminently promote the clinical comprehensive efficacy.https://oss.jomh.org/files/article/20230228-45/pdf/JOMH2022122301.pdfretrograde intrarenal surgerypercutaneous nephrolithotripsymale kidney stonesinflammatory reactionrenal functionclinical efficacy |
| spellingShingle | Bin Qin Weihao Luo Qingguo Wu Peng Yang Yiwen Liang Hanchu Ji Zhaokai Gan Effect of retrograde intrarenal surgery on the inflammatory reaction, renal function indicators and clinical efficacy in male patients with kidney stones Journal of Men's Health retrograde intrarenal surgery percutaneous nephrolithotripsy male kidney stones inflammatory reaction renal function clinical efficacy |
| title | Effect of retrograde intrarenal surgery on the inflammatory reaction, renal function indicators and clinical efficacy in male patients with kidney stones |
| title_full | Effect of retrograde intrarenal surgery on the inflammatory reaction, renal function indicators and clinical efficacy in male patients with kidney stones |
| title_fullStr | Effect of retrograde intrarenal surgery on the inflammatory reaction, renal function indicators and clinical efficacy in male patients with kidney stones |
| title_full_unstemmed | Effect of retrograde intrarenal surgery on the inflammatory reaction, renal function indicators and clinical efficacy in male patients with kidney stones |
| title_short | Effect of retrograde intrarenal surgery on the inflammatory reaction, renal function indicators and clinical efficacy in male patients with kidney stones |
| title_sort | effect of retrograde intrarenal surgery on the inflammatory reaction renal function indicators and clinical efficacy in male patients with kidney stones |
| topic | retrograde intrarenal surgery percutaneous nephrolithotripsy male kidney stones inflammatory reaction renal function clinical efficacy |
| url | https://oss.jomh.org/files/article/20230228-45/pdf/JOMH2022122301.pdf |
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