Effect of Routine Antenatal Daily Iron Supplementation on Fetal Weight

Background: To study the effect of routine antenatal daily iron supplementation on fetal weight. Methods: In this randomized control trial thirty two adult female and ten adult male Sprague- Dawley rats (weighing 200-250 gm) were taken. They were distributed randomly into two equal study groups. Fer...

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Main Author: Umbreen Noor
Format: Article
Language:English
Published: Rawalpindi Medical University 2011-06-01
Series:Journal of Rawalpindi Medical College
Subjects:
Online Access:https://www.journalrmc.com/index.php/JRMC/article/view/651
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author Umbreen Noor
author_facet Umbreen Noor
author_sort Umbreen Noor
collection DOAJ
description Background: To study the effect of routine antenatal daily iron supplementation on fetal weight. Methods: In this randomized control trial thirty two adult female and ten adult male Sprague- Dawley rats (weighing 200-250 gm) were taken. They were distributed randomly into two equal study groups. Ferrous sulphate was administered orally at 0 and 10mg/kg/day starting from gestation day (GD) 1, and half of the animals were sacrificed on GD 17 and half were sacrificed on GD 20. Five millilitre of maternal blood was taken through intracardiac route for measurement of blood haemoglobin and serum ferritin level. Maternal body weight was recorded at the start and then at the end of the experiment. Fetal weight was also recorded. Results: The results were assessed on gestational day 17 and 20. There was no significant change in the maternal weight gain and number viability of fetuses of control and experimental groups. There was an increase in the mean fetal weight, maternal haemoglobin and maternal ferritin in iron replete rats as compared to non-iron supplemented (control) rats. Conclusion: Antenatal daily iron supplementation is effective in improving fetal weight.
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spelling doaj.art-1b931f3a48734368bf1439424f8bd2dd2022-12-22T03:05:26ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702011-06-01151Effect of Routine Antenatal Daily Iron Supplementation on Fetal WeightUmbreen Noor0Anatomy Department, Army Medical College, RawalpindiBackground: To study the effect of routine antenatal daily iron supplementation on fetal weight. Methods: In this randomized control trial thirty two adult female and ten adult male Sprague- Dawley rats (weighing 200-250 gm) were taken. They were distributed randomly into two equal study groups. Ferrous sulphate was administered orally at 0 and 10mg/kg/day starting from gestation day (GD) 1, and half of the animals were sacrificed on GD 17 and half were sacrificed on GD 20. Five millilitre of maternal blood was taken through intracardiac route for measurement of blood haemoglobin and serum ferritin level. Maternal body weight was recorded at the start and then at the end of the experiment. Fetal weight was also recorded. Results: The results were assessed on gestational day 17 and 20. There was no significant change in the maternal weight gain and number viability of fetuses of control and experimental groups. There was an increase in the mean fetal weight, maternal haemoglobin and maternal ferritin in iron replete rats as compared to non-iron supplemented (control) rats. Conclusion: Antenatal daily iron supplementation is effective in improving fetal weight.https://www.journalrmc.com/index.php/JRMC/article/view/651Pregnancy,ferrous sulphate supplementationmaternal body weightfetal weight
spellingShingle Umbreen Noor
Effect of Routine Antenatal Daily Iron Supplementation on Fetal Weight
Journal of Rawalpindi Medical College
Pregnancy,
ferrous sulphate supplementation
maternal body weight
fetal weight
title Effect of Routine Antenatal Daily Iron Supplementation on Fetal Weight
title_full Effect of Routine Antenatal Daily Iron Supplementation on Fetal Weight
title_fullStr Effect of Routine Antenatal Daily Iron Supplementation on Fetal Weight
title_full_unstemmed Effect of Routine Antenatal Daily Iron Supplementation on Fetal Weight
title_short Effect of Routine Antenatal Daily Iron Supplementation on Fetal Weight
title_sort effect of routine antenatal daily iron supplementation on fetal weight
topic Pregnancy,
ferrous sulphate supplementation
maternal body weight
fetal weight
url https://www.journalrmc.com/index.php/JRMC/article/view/651
work_keys_str_mv AT umbreennoor effectofroutineantenataldailyironsupplementationonfetalweight