Dock5 Deficiency Promotes Proteinuric Kidney Diseases via Modulating Podocyte Lipid Metabolism

Dock5 Deficiency Promotes Proteinuric Kidney Diseases via Modulating Podocyte Lipid Metabolism

Abstract Podocytes are particularly sensitive to lipid accumulation, which has recently emerged as a crucial pathological process in the progression of proteinuric kidney diseases like diabetic kidney disease and focal segmental glomerulosclerosis. However, the underlying mechanism remains unclear....

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Bibliographic Details
Main Authors: Hua Qu, Xiufei Liu, Jiaran Zhu, Xin Xiong, Lu Li, Qingshan He, Yuren Wang, Guojun Yang, Linlin Zhang, Qingwu Yang, Gang Luo, Yi Zheng, Hongting Zheng
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
Dock5
lipid metabolism
podocytes
proteinuric kidney diseases
Online Access:https://doi.org/10.1002/advs.202306365

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