Longitudinal Changes in Mitochondrial DNA Copy Number and Telomere Length in Patients with Parkinson’s Disease

Longitudinal Changes in Mitochondrial DNA Copy Number and Telomere Length in Patients with Parkinson’s Disease

Parkinson’s disease (PD) pathophysiology includes mitochondrial dysfunction, neuroinflammation, and aging as its biggest risk factors. Mitochondrial DNA copy number (mtDNA-CN) and telomere length (TL) are biological aging markers with inconclusive results regarding their association with PD. A case–...

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Bibliographic Details
Main Authors: Alberto Ortega-Vázquez, Salvador Sánchez-Badajos, Miguel Ángel Ramírez-García, Diana Alvarez-Luquín, Marisol López-López, Laura Virginia Adalid-Peralta, Nancy Monroy-Jaramillo
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Genes
Subjects:
Parkinson’s disease
telomere length
mitochondrial DNA copy number
dopaminergic replacement therapy
aging
inflammatory index
Online Access:https://www.mdpi.com/2073-4425/14/10/1913

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