Three cases of heavy menstrual bleeding with uniform thickening of the junctional zone endometrium

Heavy menstrual bleeding is a type of abnormal uterine bleeding. Abnormal uterine bleeding includes the poorly characterized “not otherwise classified” category. Here, we report three abnormal uterine bleeding-not otherwise classified cases with uniform thickening of the junctional zone endometrium....

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Main Authors: Takashi Matsushima, Shunji Suzuki
Format: Article
Language:English
Published: SAGE Publishing 2023-06-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X231182803
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author Takashi Matsushima
Shunji Suzuki
author_facet Takashi Matsushima
Shunji Suzuki
author_sort Takashi Matsushima
collection DOAJ
description Heavy menstrual bleeding is a type of abnormal uterine bleeding. Abnormal uterine bleeding includes the poorly characterized “not otherwise classified” category. Here, we report three abnormal uterine bleeding-not otherwise classified cases with uniform thickening of the junctional zone endometrium. Case 1: A 33-year-old nullipara with heavy menstrual bleeding presented with severe anemia (hemoglobin: 4.7 g/dL) and an 8.4-mm junctional zone endometrium on magnetic resonance imaging. Her condition improved with iron and low-dose estradiol-progestins. Case 2: A 36-year-old nulligravida had heavy menstrual bleeding, anemia (hemoglobin: 9.5 g/dL), and a 9.4-mm junctional zone endometrium; her anemia improved with iron supplementation. Case 3: A 39-year-old multipara had heavy menstrual bleeding, anemia (hemoglobin: 9.6 g/dL), and a 12.3-mm junctional zone endometrium, and was managed with a levonorgestrel-releasing intrauterine system. Pelvic examination, transvaginal sonography, and uterine size on magnetic resonance imaging were normal in all cases. In those without uterine abnormalities, uniform thickening of the junctional zone endometrium (⩾8 mm) may trigger heavy menstrual bleeding; hence, magnetic resonance imaging may be warranted in abnormal uterine bleeding-not otherwise classified cases.
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spelling doaj.art-1b9bf4c9875340ef8be709cbaf2ed2af2023-06-21T16:04:28ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2023-06-011110.1177/2050313X231182803Three cases of heavy menstrual bleeding with uniform thickening of the junctional zone endometriumTakashi MatsushimaShunji SuzukiHeavy menstrual bleeding is a type of abnormal uterine bleeding. Abnormal uterine bleeding includes the poorly characterized “not otherwise classified” category. Here, we report three abnormal uterine bleeding-not otherwise classified cases with uniform thickening of the junctional zone endometrium. Case 1: A 33-year-old nullipara with heavy menstrual bleeding presented with severe anemia (hemoglobin: 4.7 g/dL) and an 8.4-mm junctional zone endometrium on magnetic resonance imaging. Her condition improved with iron and low-dose estradiol-progestins. Case 2: A 36-year-old nulligravida had heavy menstrual bleeding, anemia (hemoglobin: 9.5 g/dL), and a 9.4-mm junctional zone endometrium; her anemia improved with iron supplementation. Case 3: A 39-year-old multipara had heavy menstrual bleeding, anemia (hemoglobin: 9.6 g/dL), and a 12.3-mm junctional zone endometrium, and was managed with a levonorgestrel-releasing intrauterine system. Pelvic examination, transvaginal sonography, and uterine size on magnetic resonance imaging were normal in all cases. In those without uterine abnormalities, uniform thickening of the junctional zone endometrium (⩾8 mm) may trigger heavy menstrual bleeding; hence, magnetic resonance imaging may be warranted in abnormal uterine bleeding-not otherwise classified cases.https://doi.org/10.1177/2050313X231182803
spellingShingle Takashi Matsushima
Shunji Suzuki
Three cases of heavy menstrual bleeding with uniform thickening of the junctional zone endometrium
SAGE Open Medical Case Reports
title Three cases of heavy menstrual bleeding with uniform thickening of the junctional zone endometrium
title_full Three cases of heavy menstrual bleeding with uniform thickening of the junctional zone endometrium
title_fullStr Three cases of heavy menstrual bleeding with uniform thickening of the junctional zone endometrium
title_full_unstemmed Three cases of heavy menstrual bleeding with uniform thickening of the junctional zone endometrium
title_short Three cases of heavy menstrual bleeding with uniform thickening of the junctional zone endometrium
title_sort three cases of heavy menstrual bleeding with uniform thickening of the junctional zone endometrium
url https://doi.org/10.1177/2050313X231182803
work_keys_str_mv AT takashimatsushima threecasesofheavymenstrualbleedingwithuniformthickeningofthejunctionalzoneendometrium
AT shunjisuzuki threecasesofheavymenstrualbleedingwithuniformthickeningofthejunctionalzoneendometrium