Valine/isoleucine variants drive selective pressure in the VP1 sequence of EV-A71 enteroviruses

Valine/isoleucine variants drive selective pressure in the VP1 sequence of EV-A71 enteroviruses

Abstract Background In 2011–2012, Northern Vietnam experienced its first large scale hand foot and mouth disease (HFMD) epidemic. In 2011, a major HFMD epidemic was also reported in South Vietnam with fatal cases. This 2011–2012 outbreak was the first one to occur in North Vietnam providing grounds...

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Bibliographic Details
Main Authors: Nghia Ngu Duy, Le Thi Thanh Huong, Patrice Ravel, Le Thi Song Huong, Ankit Dwivedi, October Michael Sessions, Yan’An Hou, Robert Chua, Guilhem Kister, Aneta Afelt, Catherine Moulia, Duane J. Gubler, Vu Dinh Thiem, Nguyen Thi Hien Thanh, Christian Devaux, Tran Nhu Duong, Nguyen Tran Hien, Emmanuel Cornillot, Laurent Gavotte, Roger Frutos
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Infectious Diseases
Subjects:
VP1
HFMD
Enterovirus
EV-A71
Vietnam
Online Access:http://link.springer.com/article/10.1186/s12879-017-2427-4

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