A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology

A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology

Abstract Background Extracellular vesicles (EVs), including small EVs (sEVs) such as exosomes, exhibit great potential for the diagnosis and treatment of brain disorders, representing a valuable tool for precision medicine. The latter demands high-quality human biospecimens, especially in complex di...

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Bibliographic Details
Main Authors: Patrícia A. Gomes, Cristian Bodo, Carlos Nogueras-Ortiz, Martina Samiotaki, Minghao Chen, Carina Soares-Cunha, Joana M. Silva, Bárbara Coimbra, George Stamatakis, Liliana Santos, George Panayotou, Foteini Tzouanou, Clarissa L. Waites, Christos Gatsogiannis, Nuno Sousa, Dimitrios Kapogiannis, Bruno Costa-Silva, Ioannis Sotiropoulos
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cell Communication and Signaling
Subjects:
Extracellular vesicles
Brain
Exosomes
Human
Mouse
Spontaneous release
Online Access:https://doi.org/10.1186/s12964-023-01045-z

Internet

https://doi.org/10.1186/s12964-023-01045-z

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