Differential pulmonary toxicity and autoantibody formation in genetically distinct mouse strains following combined exposure to silica and diesel exhaust particles

Differential pulmonary toxicity and autoantibody formation in genetically distinct mouse strains following combined exposure to silica and diesel exhaust particles

Abstract Background Inhalation of airborne particulate matter, such as silica and diesel exhaust particles, poses serious long-term respiratory and systemic health risks. Silica exposure can lead to silicosis and systemic autoimmune diseases, while DEP exposure is linked to asthma and cancer. Combin...

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Bibliographic Details
Main Authors: Lisa MF Janssen, Frauke Lemaire, Nora Fopke Marain, Steven Ronsmans, Natasja Heylen, Arno Vanstapel, Greetje Vande Velde, Jeroen AJ Vanoirbeek, Kenneth Michael Pollard, Manosij Ghosh, Peter HM Hoet
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Particle and Fibre Toxicology
Subjects:
Silica
Silicosis
Diesel exhaust particles
Autoimmunity
Mice
Lung inflammation
Online Access:https://doi.org/10.1186/s12989-024-00569-7

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