Prognostic Relevance of <i>NPM1</i> and <i>FLT3</i> Mutations in Acute Myeloid Leukaemia, Longterm Follow-Up—A Single Center Experience

Prognostic Relevance of <i>NPM1</i> and <i>FLT3</i> Mutations in Acute Myeloid Leukaemia, Longterm Follow-Up—A Single Center Experience

The prognosis of acute myeloid leukemia depends on genetic aberrations, particularly <i>NPM1</i> and <i>FLT3</i>-ITD mutations. The targeted drugs’ availability has renewed interest in <i>FLT3</i> mutations, but the impact of these genetic alterations using these...

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Bibliographic Details
Main Authors: Erika Borlenghi, Chiara Cattaneo, Diego Bertoli, Elisa Cerqui, Silvana Archetti, Angela Passi, Margherita Oberti, Tatiana Zollner, Carlotta Giupponi, Chiara Pagani, Nicola Bianchetti, Chiara Bottelli, Samuele Bagnasco, Margherita Sciumè, Alessandra Tucci, Giuseppe Rossi
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
acute myeloid leukaemia
high dose cytarabine (HD-ARAC)
idarubicin
<i>FLT3</i> mutation
<i>NPM1</i> mutation
Online Access:https://www.mdpi.com/2072-6694/14/19/4716

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