Association of Office and Ambulatory Blood Pressure with Left Ventricular Structure and Function in Hypertensive Patients
Zhuo Sang, Xianli Zeng, Xiaohui Yuan, Xiaolin Wang, Liancong Fu, Wenwen Zhuang Department of General Practice, Huizhou Municipal Central Hospital, Huizhou, Guangdong, People’s Republic of ChinaCorrespondence: Zhuo Sang, Department of General Practice, Huizhou Municipal Central Hospital, Huizhou, Gua...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-05-01
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| Series: | International Journal of General Medicine |
| Subjects: | |
| Online Access: | https://www.dovepress.com/association-of-office-and-ambulatory-blood-pressure-with-left-ventricu-peer-reviewed-fulltext-article-IJGM |
| _version_ | 1811252228647813120 |
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| author | Sang Z Zeng X Yuan X Wang X Fu L Zhuang W |
| author_facet | Sang Z Zeng X Yuan X Wang X Fu L Zhuang W |
| author_sort | Sang Z |
| collection | DOAJ |
| description | Zhuo Sang, Xianli Zeng, Xiaohui Yuan, Xiaolin Wang, Liancong Fu, Wenwen Zhuang Department of General Practice, Huizhou Municipal Central Hospital, Huizhou, Guangdong, People’s Republic of ChinaCorrespondence: Zhuo Sang, Department of General Practice, Huizhou Municipal Central Hospital, Huizhou, Guangdong, People’s Republic of China, Tel +86-752-2288288, Email 116920609@qq.comObjective: The current study was to evaluate the association of office blood pressure (OBP) and 24h ambulatory blood pressure (ABP) with left ventricular (LV) structure and function in hypertensive patients. Whether the association was modified by sex was also evaluated.Methods: A total of 694 hypertensive patients without cardiovascular disease were retrospectively included from the inpatient clinic. Regression analysis was performed to evaluate the association of OBP and 24h ABP parameters with LV mass index (LVMi), e’ velocity and left ventricular hypertrophy (LVH) with adjustment for covariates including age, obesity, diabetes mellitus, obstructive sleep apnea, estimated glomerular filtration rate and antihypertensive drugs.Results: There was no difference in OBP by sex. Compared to women, men had a higher 24h (132.6 ± 11.3 vs 129.3 ± 10.0 mm Hg), daytime (136.6 ± 12.9 vs 132.8 ± 9.5 mm Hg) and nighttime (130.3 ± 9.2 vs 125.1 ± 6.6 mm Hg) SBP. The proportion of patients with non-dipping pattern and reverse dipper pattern was also higher in men. In the overall participants, 24h, daytime and nighttime SBP, non-dipping and reverse dipper pattern were associated with LVMi, e’ velocity and LVH, which were not observed in OBP. The magnitude of the association between 24h, daytime and nighttime SBP, non-dipping and reverse dipper pattern with LVMi, e’ velocity and LVH was stronger in men than in women (P-value for interaction < 0.05).Conclusion: Twenty-four-hour ABP appears to be better than OBP in association with LV structural and functional alterations, and this association was modified by sex.Keywords: office blood pressure, ambulatory blood pressure, sex, cardiac structure, cardiac function |
| first_indexed | 2024-04-12T16:32:40Z |
| format | Article |
| id | doaj.art-1ba223c2337b4de6b476f0380eda19db |
| institution | Directory Open Access Journal |
| issn | 1178-7074 |
| language | English |
| last_indexed | 2024-04-12T16:32:40Z |
| publishDate | 2022-05-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of General Medicine |
| spelling | doaj.art-1ba223c2337b4de6b476f0380eda19db2022-12-22T03:25:06ZengDove Medical PressInternational Journal of General Medicine1178-70742022-05-01Volume 154649465675062Association of Office and Ambulatory Blood Pressure with Left Ventricular Structure and Function in Hypertensive PatientsSang ZZeng XYuan XWang XFu LZhuang WZhuo Sang, Xianli Zeng, Xiaohui Yuan, Xiaolin Wang, Liancong Fu, Wenwen Zhuang Department of General Practice, Huizhou Municipal Central Hospital, Huizhou, Guangdong, People’s Republic of ChinaCorrespondence: Zhuo Sang, Department of General Practice, Huizhou Municipal Central Hospital, Huizhou, Guangdong, People’s Republic of China, Tel +86-752-2288288, Email 116920609@qq.comObjective: The current study was to evaluate the association of office blood pressure (OBP) and 24h ambulatory blood pressure (ABP) with left ventricular (LV) structure and function in hypertensive patients. Whether the association was modified by sex was also evaluated.Methods: A total of 694 hypertensive patients without cardiovascular disease were retrospectively included from the inpatient clinic. Regression analysis was performed to evaluate the association of OBP and 24h ABP parameters with LV mass index (LVMi), e’ velocity and left ventricular hypertrophy (LVH) with adjustment for covariates including age, obesity, diabetes mellitus, obstructive sleep apnea, estimated glomerular filtration rate and antihypertensive drugs.Results: There was no difference in OBP by sex. Compared to women, men had a higher 24h (132.6 ± 11.3 vs 129.3 ± 10.0 mm Hg), daytime (136.6 ± 12.9 vs 132.8 ± 9.5 mm Hg) and nighttime (130.3 ± 9.2 vs 125.1 ± 6.6 mm Hg) SBP. The proportion of patients with non-dipping pattern and reverse dipper pattern was also higher in men. In the overall participants, 24h, daytime and nighttime SBP, non-dipping and reverse dipper pattern were associated with LVMi, e’ velocity and LVH, which were not observed in OBP. The magnitude of the association between 24h, daytime and nighttime SBP, non-dipping and reverse dipper pattern with LVMi, e’ velocity and LVH was stronger in men than in women (P-value for interaction < 0.05).Conclusion: Twenty-four-hour ABP appears to be better than OBP in association with LV structural and functional alterations, and this association was modified by sex.Keywords: office blood pressure, ambulatory blood pressure, sex, cardiac structure, cardiac functionhttps://www.dovepress.com/association-of-office-and-ambulatory-blood-pressure-with-left-ventricu-peer-reviewed-fulltext-article-IJGMoffice blood pressureambulatory blood pressuresexcardiac structurecardiac function |
| spellingShingle | Sang Z Zeng X Yuan X Wang X Fu L Zhuang W Association of Office and Ambulatory Blood Pressure with Left Ventricular Structure and Function in Hypertensive Patients International Journal of General Medicine office blood pressure ambulatory blood pressure sex cardiac structure cardiac function |
| title | Association of Office and Ambulatory Blood Pressure with Left Ventricular Structure and Function in Hypertensive Patients |
| title_full | Association of Office and Ambulatory Blood Pressure with Left Ventricular Structure and Function in Hypertensive Patients |
| title_fullStr | Association of Office and Ambulatory Blood Pressure with Left Ventricular Structure and Function in Hypertensive Patients |
| title_full_unstemmed | Association of Office and Ambulatory Blood Pressure with Left Ventricular Structure and Function in Hypertensive Patients |
| title_short | Association of Office and Ambulatory Blood Pressure with Left Ventricular Structure and Function in Hypertensive Patients |
| title_sort | association of office and ambulatory blood pressure with left ventricular structure and function in hypertensive patients |
| topic | office blood pressure ambulatory blood pressure sex cardiac structure cardiac function |
| url | https://www.dovepress.com/association-of-office-and-ambulatory-blood-pressure-with-left-ventricu-peer-reviewed-fulltext-article-IJGM |
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