Multiplex Immunofluorescence and the Digital Image Analysis Workflow for Evaluation of the Tumor Immune Environment in Translational Research

Multiplex Immunofluorescence and the Digital Image Analysis Workflow for Evaluation of the Tumor Immune Environment in Translational Research

A robust understanding of the tumor immune environment has important implications for cancer diagnosis, prognosis, research, and immunotherapy. Traditionally, immunohistochemistry (IHC) has been regarded as the standard method for detecting proteins in situ, but this technique allows for the evaluat...

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Bibliographic Details
Main Authors: Frank Rojas, Sharia Hernandez, Rossana Lazcano, Caddie Laberiano-Fernandez, Edwin Roger Parra
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
immunotherapy
multiplex immunofluorescence
image analysis algorithms
tissue
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.889886/full

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