Ultrasound-Guided Injection of Botulinum Toxin Type A for Piriformis Muscle Syndrome: A Case Report and Review of the Literature

Piriformis muscle syndrome (PMS) is caused by prolonged or excessive contraction of the piriformis muscle associated with pain in the buttocks, hips, and lower limbs because of the close proximity to the sciatic nerve. Botulinum toxin type A (BoNT-A) reduces muscle hypertonia as well as muscle contr...

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Main Authors: Andrea Santamato, Maria Francesca Micello, Giovanni Valeno, Raffaele Beatrice, Nicoletta Cinone, Alessio Baricich, Alessandro Picelli, Francesco Panza, Giancarlo Logroscino, Pietro Fiore, Maurizio Ranieri
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/7/8/3045
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author Andrea Santamato
Maria Francesca Micello
Giovanni Valeno
Raffaele Beatrice
Nicoletta Cinone
Alessio Baricich
Alessandro Picelli
Francesco Panza
Giancarlo Logroscino
Pietro Fiore
Maurizio Ranieri
author_facet Andrea Santamato
Maria Francesca Micello
Giovanni Valeno
Raffaele Beatrice
Nicoletta Cinone
Alessio Baricich
Alessandro Picelli
Francesco Panza
Giancarlo Logroscino
Pietro Fiore
Maurizio Ranieri
author_sort Andrea Santamato
collection DOAJ
description Piriformis muscle syndrome (PMS) is caused by prolonged or excessive contraction of the piriformis muscle associated with pain in the buttocks, hips, and lower limbs because of the close proximity to the sciatic nerve. Botulinum toxin type A (BoNT-A) reduces muscle hypertonia as well as muscle contracture and pain inhibiting substance P release and other inflammatory factors. BoNT-A injection technique is important considering the difficult access of the needle for deep location, the small size of the muscle, and the proximity to neurovascular structures. Ultrasound guidance is easy to use and painless and several studies describe its use during BoNT-A administration in PMS. In the present review article, we briefly updated current knowledge regarding the BoNT therapy of PMS, describing also a case report in which this syndrome was treated with an ultrasound-guided injection of incobotulinumtoxin A. Pain reduction with an increase of hip articular range of motion in this patient with PMS confirmed the effectiveness of BoNT-A injection for the management of this syndrome.
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spelling doaj.art-1ba90f2270dc458ebbe3ecdf8bf6f3a22022-12-22T02:54:33ZengMDPI AGToxins2072-66512015-08-01783045305610.3390/toxins7083045toxins7083045Ultrasound-Guided Injection of Botulinum Toxin Type A for Piriformis Muscle Syndrome: A Case Report and Review of the LiteratureAndrea Santamato0Maria Francesca Micello1Giovanni Valeno2Raffaele Beatrice3Nicoletta Cinone4Alessio Baricich5Alessandro Picelli6Francesco Panza7Giancarlo Logroscino8Pietro Fiore9Maurizio Ranieri10Physical Medicine and Rehabilitation Section, "OORR" Hospital, University of Foggia, Foggia 71100, ItalyPhysical Medicine and Rehabilitation Section, "OORR" Hospital, University of Foggia, Foggia 71100, ItalyPhysical Medicine and Rehabilitation Section, "OORR" Hospital, University of Foggia, Foggia 71100, ItalyPhysical Medicine and Rehabilitation Section, "OORR" Hospital, University of Foggia, Foggia 71100, ItalyPhysical Medicine and Rehabilitation Section, "OORR" Hospital, University of Foggia, Foggia 71100, ItalyPhysical Medicine and Rehabilitation, Department of Health Sciences, University of Eastern Piedmont, Novara 28100, ItalyNeuromotor and Cognitive Rehabilitation Research Center, Department of Neurological, Biomedical and Movement Sciences, University of Verona, Verona 37134, ItalyNeurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari 70120, ItalyNeurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari 70120, ItalyDepartment of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari 70120, ItalyPhysical Medicine and Rehabilitation Section, "OORR" Hospital, University of Foggia, Foggia 71100, ItalyPiriformis muscle syndrome (PMS) is caused by prolonged or excessive contraction of the piriformis muscle associated with pain in the buttocks, hips, and lower limbs because of the close proximity to the sciatic nerve. Botulinum toxin type A (BoNT-A) reduces muscle hypertonia as well as muscle contracture and pain inhibiting substance P release and other inflammatory factors. BoNT-A injection technique is important considering the difficult access of the needle for deep location, the small size of the muscle, and the proximity to neurovascular structures. Ultrasound guidance is easy to use and painless and several studies describe its use during BoNT-A administration in PMS. In the present review article, we briefly updated current knowledge regarding the BoNT therapy of PMS, describing also a case report in which this syndrome was treated with an ultrasound-guided injection of incobotulinumtoxin A. Pain reduction with an increase of hip articular range of motion in this patient with PMS confirmed the effectiveness of BoNT-A injection for the management of this syndrome.http://www.mdpi.com/2072-6651/7/8/3045piriformis muscle syndromebotulinum toxin type Aultrasound guide
spellingShingle Andrea Santamato
Maria Francesca Micello
Giovanni Valeno
Raffaele Beatrice
Nicoletta Cinone
Alessio Baricich
Alessandro Picelli
Francesco Panza
Giancarlo Logroscino
Pietro Fiore
Maurizio Ranieri
Ultrasound-Guided Injection of Botulinum Toxin Type A for Piriformis Muscle Syndrome: A Case Report and Review of the Literature
Toxins
piriformis muscle syndrome
botulinum toxin type A
ultrasound guide
title Ultrasound-Guided Injection of Botulinum Toxin Type A for Piriformis Muscle Syndrome: A Case Report and Review of the Literature
title_full Ultrasound-Guided Injection of Botulinum Toxin Type A for Piriformis Muscle Syndrome: A Case Report and Review of the Literature
title_fullStr Ultrasound-Guided Injection of Botulinum Toxin Type A for Piriformis Muscle Syndrome: A Case Report and Review of the Literature
title_full_unstemmed Ultrasound-Guided Injection of Botulinum Toxin Type A for Piriformis Muscle Syndrome: A Case Report and Review of the Literature
title_short Ultrasound-Guided Injection of Botulinum Toxin Type A for Piriformis Muscle Syndrome: A Case Report and Review of the Literature
title_sort ultrasound guided injection of botulinum toxin type a for piriformis muscle syndrome a case report and review of the literature
topic piriformis muscle syndrome
botulinum toxin type A
ultrasound guide
url http://www.mdpi.com/2072-6651/7/8/3045
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