Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms
Abstract Treating an abdominal aortic aneurysm (AAA) with a stent graft (SG) and a multilayer stent (MS) is a key technology in isolating flow fields. Clinically, dual stents (an SG in the proximal and an MS in the distal of AAA) are used for treatment of AAA, but only a few studies have examined th...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2018-11-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-018-34354-2 |
| _version_ | 1818345826312781824 |
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| author | Yuan Ding Li Zhongyou Jiang Wentao Zhang Yinci Wang Zhenze Chen Yu |
| author_facet | Yuan Ding Li Zhongyou Jiang Wentao Zhang Yinci Wang Zhenze Chen Yu |
| author_sort | Yuan Ding |
| collection | DOAJ |
| description | Abstract Treating an abdominal aortic aneurysm (AAA) with a stent graft (SG) and a multilayer stent (MS) is a key technology in isolating flow fields. Clinically, dual stents (an SG in the proximal and an MS in the distal of AAA) are used for treatment of AAA, but only a few studies have examined the relationship between SG coverage and treatment effects. Through numerical simulation of the hemodynamics after SG and MS implantation, the SG coverage and position were simulated at 0% (0 mm), 25% (13.75 mm), 50% (27.5 mm), and 75% (41.25 mm). With increasing SG coverage, the pressure on the aneurysm sac wall and the flow of branch vessels gradually decreased, and the lower wall shear stress (WSS) gradually increased. The changes in pressure, lower WSS, and the mass flow rate of the branch vessels did not change significantly. The coverage of the SG has a nonsignificant effect on hemodynamics in the treatment of AAA; the implantation position need not be very precise. This research can provide theoretic support for clinicians’ decision-making. |
| first_indexed | 2024-12-13T17:08:32Z |
| format | Article |
| id | doaj.art-1ba9ac1308d74dcab39af96be30bee7b |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-13T17:08:32Z |
| publishDate | 2018-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-1ba9ac1308d74dcab39af96be30bee7b2022-12-21T23:37:37ZengNature PortfolioScientific Reports2045-23222018-11-01811610.1038/s41598-018-34354-2Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysmsYuan Ding0Li Zhongyou1Jiang Wentao2Zhang Yinci3Wang Zhenze4Chen Yu5Department of Vascular Surgery of West China Hospital, Sichuan UniversityDepartment of Applied Mechanics, Sichuan UniversityDepartment of Applied Mechanics, Sichuan UniversitySchool of Computer science, Sichuan University of Science and EngineeringKey Laboratory of Rehabilitation Technical Aids Technology and System of the Ministry of Civil Affairs & Beijing Key Laboratory of Rehabilitation Technical Aids for Old-Age Disability, National Research Center for Rehabilitation Technical AidsDepartment of Applied Mechanics, Sichuan UniversityAbstract Treating an abdominal aortic aneurysm (AAA) with a stent graft (SG) and a multilayer stent (MS) is a key technology in isolating flow fields. Clinically, dual stents (an SG in the proximal and an MS in the distal of AAA) are used for treatment of AAA, but only a few studies have examined the relationship between SG coverage and treatment effects. Through numerical simulation of the hemodynamics after SG and MS implantation, the SG coverage and position were simulated at 0% (0 mm), 25% (13.75 mm), 50% (27.5 mm), and 75% (41.25 mm). With increasing SG coverage, the pressure on the aneurysm sac wall and the flow of branch vessels gradually decreased, and the lower wall shear stress (WSS) gradually increased. The changes in pressure, lower WSS, and the mass flow rate of the branch vessels did not change significantly. The coverage of the SG has a nonsignificant effect on hemodynamics in the treatment of AAA; the implantation position need not be very precise. This research can provide theoretic support for clinicians’ decision-making.https://doi.org/10.1038/s41598-018-34354-2Thoracoabdominal Aortic AneurysmSG CoverageMultilayer Stent (MS)Blood Vessel BranchesDual Stent |
| spellingShingle | Yuan Ding Li Zhongyou Jiang Wentao Zhang Yinci Wang Zhenze Chen Yu Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms Scientific Reports Thoracoabdominal Aortic Aneurysm SG Coverage Multilayer Stent (MS) Blood Vessel Branches Dual Stent |
| title | Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
| title_full | Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
| title_fullStr | Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
| title_full_unstemmed | Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
| title_short | Stent graft coverage of dual-stent strategy in the management of abdominal aortic aneurysms |
| title_sort | stent graft coverage of dual stent strategy in the management of abdominal aortic aneurysms |
| topic | Thoracoabdominal Aortic Aneurysm SG Coverage Multilayer Stent (MS) Blood Vessel Branches Dual Stent |
| url | https://doi.org/10.1038/s41598-018-34354-2 |
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