The Role of Response-Shift in Studies Assessing Quality of Life Outcomes Among Cancer Patients: A Systematic Review
Objective: Response-shift has been cited as an important measurement consideration when assessing patient reported quality of life (QoL) outcomes over time among patients with severe chronic conditions. Here we report the results of a systematic review of response shift in studies assessing QoL amon...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-08-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2019.00783/full |
| _version_ | 1811299196299378688 |
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| author | Gabriela Ilie Gabriela Ilie Gabriela Ilie Gabriela Ilie Jillian Bradfield Louise Moodie Tarek Lawen Tarek Lawen Alzena Ilie Zeina Lawen Chloe Blackman Ryan Gainer Robert D. H. Rutledge Robert D. H. Rutledge |
| author_facet | Gabriela Ilie Gabriela Ilie Gabriela Ilie Gabriela Ilie Jillian Bradfield Louise Moodie Tarek Lawen Tarek Lawen Alzena Ilie Zeina Lawen Chloe Blackman Ryan Gainer Robert D. H. Rutledge Robert D. H. Rutledge |
| author_sort | Gabriela Ilie |
| collection | DOAJ |
| description | Objective: Response-shift has been cited as an important measurement consideration when assessing patient reported quality of life (QoL) outcomes over time among patients with severe chronic conditions. Here we report the results of a systematic review of response shift in studies assessing QoL among cancer patients.Methods: A systematic review using MEDLINE, EMBASE, and PsychINFO along with a manual search of the cited references of the articles selected, was conducted. A quality review was performed using STROBE criteria and reported according to PRISMA guidelines.Results: A systematic review of 1,487 records published between 1,887 and December 2018 revealed 104 potentially eligible studies, and 35 studies met inclusion criteria for content and quality. The most common cancer patient populations investigated in these studies were breast (18 studies), lung (14 studies), prostate (eight studies), and colorectal (eight studies). Response shift was identified among 34 of the 35 studies reviewed. Effect sizes were reported in 17 studies assessing QoL outcomes among cancer patients; 12 of which had negligible to small effect sizes, four reported medium effect sizes which were related to physical, global QoL, pain, and social (role) functioning and one reported a large effect size (fatigue). The most prevalent method for assessing response shift was the then-test, which is prone to recall bias, followed by the pre-test and post-test method. Given the heterogeneity among the characteristics of the samples and designs reviewed, as well as the overall small to negligible effect sizes for the effects reported, conclusions stating that changes due to internal cognitive shifts in perceived QoL should account for changes observed in cancer patients' QoL outcomes should be interpreted with caution.Conclusion: Further work is needed in this area of research. Future studies should control for patient characteristics, time elapsed between diagnosis and baseline assessment and evaluate their contribution to the presence of response shift. Time between assessments should include short and longer periods between assessments and evaluate whether the presence of response shift holds over time. Possible avenues for inquiry for future investigation are discussed. |
| first_indexed | 2024-04-13T06:31:40Z |
| format | Article |
| id | doaj.art-1baa846a833041a4b26028720a2bb19c |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-13T06:31:40Z |
| publishDate | 2019-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-1baa846a833041a4b26028720a2bb19c2022-12-22T02:58:05ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2019-08-01910.3389/fonc.2019.00783474005The Role of Response-Shift in Studies Assessing Quality of Life Outcomes Among Cancer Patients: A Systematic ReviewGabriela Ilie0Gabriela Ilie1Gabriela Ilie2Gabriela Ilie3Jillian Bradfield4Louise Moodie5Tarek Lawen6Tarek Lawen7Alzena Ilie8Zeina Lawen9Chloe Blackman10Ryan Gainer11Robert D. H. Rutledge12Robert D. H. Rutledge13Department of Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, Halifax Regional Municipality, NS, CanadaDepartment of Urology, Faculty of Medicine, Dalhousie University, Halifax Regional Municipality, NS, CanadaDepartment of Psychology and Neuroscience, Dalhousie University, Halifax Regional Municipality, NS, CanadaDepartment of Radiation Oncology, Faculty of Medicine, Dalhousie University, Halifax Regional Municipality, NS, CanadaDepartment of Psychology and Neuroscience, Dalhousie University, Halifax Regional Municipality, NS, CanadaDepartment of Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, Halifax Regional Municipality, NS, CanadaDepartment of Urology, Faculty of Medicine, Dalhousie University, Halifax Regional Municipality, NS, CanadaUrology, Halifax Infirmary—QEII—Nova Scotia Health Authority, Halifax Regional Municipality, NS, CanadaDepartment of Psychology and Neuroscience, Dalhousie University, Halifax Regional Municipality, NS, CanadaDepartment of Psychology and Neuroscience, Dalhousie University, Halifax Regional Municipality, NS, CanadaDepartment of Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, Halifax Regional Municipality, NS, CanadaDepartment of Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, Halifax Regional Municipality, NS, CanadaDepartment of Radiation Oncology, Faculty of Medicine, Dalhousie University, Halifax Regional Municipality, NS, CanadaNova Scotia Cancer Centre, Queen Elizabeth II Health Sciences Centre, Halifax Regional Municipality, NS, CanadaObjective: Response-shift has been cited as an important measurement consideration when assessing patient reported quality of life (QoL) outcomes over time among patients with severe chronic conditions. Here we report the results of a systematic review of response shift in studies assessing QoL among cancer patients.Methods: A systematic review using MEDLINE, EMBASE, and PsychINFO along with a manual search of the cited references of the articles selected, was conducted. A quality review was performed using STROBE criteria and reported according to PRISMA guidelines.Results: A systematic review of 1,487 records published between 1,887 and December 2018 revealed 104 potentially eligible studies, and 35 studies met inclusion criteria for content and quality. The most common cancer patient populations investigated in these studies were breast (18 studies), lung (14 studies), prostate (eight studies), and colorectal (eight studies). Response shift was identified among 34 of the 35 studies reviewed. Effect sizes were reported in 17 studies assessing QoL outcomes among cancer patients; 12 of which had negligible to small effect sizes, four reported medium effect sizes which were related to physical, global QoL, pain, and social (role) functioning and one reported a large effect size (fatigue). The most prevalent method for assessing response shift was the then-test, which is prone to recall bias, followed by the pre-test and post-test method. Given the heterogeneity among the characteristics of the samples and designs reviewed, as well as the overall small to negligible effect sizes for the effects reported, conclusions stating that changes due to internal cognitive shifts in perceived QoL should account for changes observed in cancer patients' QoL outcomes should be interpreted with caution.Conclusion: Further work is needed in this area of research. Future studies should control for patient characteristics, time elapsed between diagnosis and baseline assessment and evaluate their contribution to the presence of response shift. Time between assessments should include short and longer periods between assessments and evaluate whether the presence of response shift holds over time. Possible avenues for inquiry for future investigation are discussed.https://www.frontiersin.org/article/10.3389/fonc.2019.00783/fullcancersurvivorshipcancer patientsresponse-shiftquality of lifepatient reported outcomes |
| spellingShingle | Gabriela Ilie Gabriela Ilie Gabriela Ilie Gabriela Ilie Jillian Bradfield Louise Moodie Tarek Lawen Tarek Lawen Alzena Ilie Zeina Lawen Chloe Blackman Ryan Gainer Robert D. H. Rutledge Robert D. H. Rutledge The Role of Response-Shift in Studies Assessing Quality of Life Outcomes Among Cancer Patients: A Systematic Review Frontiers in Oncology cancer survivorship cancer patients response-shift quality of life patient reported outcomes |
| title | The Role of Response-Shift in Studies Assessing Quality of Life Outcomes Among Cancer Patients: A Systematic Review |
| title_full | The Role of Response-Shift in Studies Assessing Quality of Life Outcomes Among Cancer Patients: A Systematic Review |
| title_fullStr | The Role of Response-Shift in Studies Assessing Quality of Life Outcomes Among Cancer Patients: A Systematic Review |
| title_full_unstemmed | The Role of Response-Shift in Studies Assessing Quality of Life Outcomes Among Cancer Patients: A Systematic Review |
| title_short | The Role of Response-Shift in Studies Assessing Quality of Life Outcomes Among Cancer Patients: A Systematic Review |
| title_sort | role of response shift in studies assessing quality of life outcomes among cancer patients a systematic review |
| topic | cancer survivorship cancer patients response-shift quality of life patient reported outcomes |
| url | https://www.frontiersin.org/article/10.3389/fonc.2019.00783/full |
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