Magnetic Solid-Phase Microextraction Protocol Based on Didodecyldimethylammonium Bromide-Functionalized Nanoparticles for the Quantification of Epirubicin in Biological Matrices

Magnetic Solid-Phase Microextraction Protocol Based on Didodecyldimethylammonium Bromide-Functionalized Nanoparticles for the Quantification of Epirubicin in Biological Matrices

Due to epirubicin’s (EPI) narrow therapeutic index and risk of cardiotoxicity, it is critical to monitor concentrations of this drug when being used to treat cancer patients. In this study, a simple and fast magnetic solid-phase microextraction (MSPME) protocol for the determination of EPI in plasma...

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Bibliographic Details
Main Authors: Natalia Treder, Natalia Szuszczewicz, Anna Roszkowska, Ilona Olędzka, Tomasz Bączek, Ewa Bień, Małgorzata Anna Krawczyk, Alina Plenis
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
epirubicin
magnetic solid-phase microextraction
nanoparticles
validation
drug monitoring
Online Access:https://www.mdpi.com/1999-4923/15/4/1227

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