Fecal Microbiota Signatures Are Associated with Response to Ustekinumab Therapy among Crohn’s Disease Patients

Fecal Microbiota Signatures Are Associated with Response to Ustekinumab Therapy among Crohn’s Disease Patients

ABSTRACT The fecal microbiota is a rich source of biomarkers that have previously been shown to be predictive of numerous disease states. Less well studied is the effect of immunomodulatory therapy on the microbiota and its role in response to therapy. This study explored associations between the fe...

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Bibliographic Details
Main Authors: Matthew K. Doherty, Tao Ding, Charlie Koumpouras, Shannon E. Telesco, Calixte Monast, Anuk Das, Carrie Brodmerkel, Patrick D. Schloss
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mBio
Subjects:
IBD
Stelara
biologics
biomarkers
inflammatory bowel disease
machine learning
Online Access:https://journals.asm.org/doi/10.1128/mBio.02120-17

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