Medium- and long-term effects of endovascular treatments for severely stenotic basilar arteries supported by multimodal imaging
Abstract Background To evaluate the medium-and long-term effect of intravascular interventional therapy for symptomatic severe basilar artery stenosis supported by multimodal imaging. Method After strict screening of 67 patients with symptomatic severe basilar artery stenosis (70–99%) with atheroscl...
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| Format: | Article |
| Language: | English |
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BMC
2020-07-01
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| Series: | BMC Neurology |
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| Online Access: | http://link.springer.com/article/10.1186/s12883-020-01863-5 |
| _version_ | 1811331570896732160 |
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| author | Yuanzhi Li Zhenfa Li Ligang Song Weimin Xie Xianghao Gong Dongliang He Xin Zhang |
| author_facet | Yuanzhi Li Zhenfa Li Ligang Song Weimin Xie Xianghao Gong Dongliang He Xin Zhang |
| author_sort | Yuanzhi Li |
| collection | DOAJ |
| description | Abstract Background To evaluate the medium-and long-term effect of intravascular interventional therapy for symptomatic severe basilar artery stenosis supported by multimodal imaging. Method After strict screening of 67 patients with symptomatic severe basilar artery stenosis (70–99%) with atherosclerotic stenosis, 67 patients with symptomatic recurrence after intensive drug treatment were treated with intravascular balloon dilatation and Enterprise stent implantation. Any stroke or death within 30 days after operation and any stroke and restenosis during medium-and long-term follow-up were recorded. Results ①The mean age of 67 patients (67lesions) was 57 ± 8 years old, and the technical success rate was 100%; ②Preoperative angiography showed that the collateral circulation was poor, and TICI was 1-2a while postoperative angiography showed that TICI was significantly improved to 2b-3; ③The average preoperative stenosis rate was 82 ± 9%, and the postoperative stenosis rate was reduced to 17 ± 10%; ④Before surgery, abnormal perfusion was found in the posterior circulation CTP; After the postoperative re-examination, the posterior circulation of CTP perfusion was significantly improved; ⑤Postoperative symptoms and neurological conditions improved significantly; ⑥Complications of perforating branch event occurred in 1 case after operation, and symptoms were relieved after more than 1 month of medication treatment, and mild neurological dysfunction remained. 1 case developed subacute thrombosis in the stent, which improved after active intra-arterial thrombolysis, and there was no residual neurological dysfunction; and 1 case of micro-guide wire being trapped by the distal vasospasm. ⑦67 patients were followed up by telephone, WeChat or imaging for 36–66 months. Conclusions In summary intravascular balloon dilation + Enterprise stent implantation is safe and effective for the treatment of symptomatic severe atherosclerotic stenosis of the basilar artery, with high technical success rate, low perioperative complications, and good mid-term and long-term effects. |
| first_indexed | 2024-04-13T16:22:38Z |
| format | Article |
| id | doaj.art-1babf7ca6f714c30892a48cb089cf270 |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-04-13T16:22:38Z |
| publishDate | 2020-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-1babf7ca6f714c30892a48cb089cf2702022-12-22T02:39:51ZengBMCBMC Neurology1471-23772020-07-012011810.1186/s12883-020-01863-5Medium- and long-term effects of endovascular treatments for severely stenotic basilar arteries supported by multimodal imagingYuanzhi Li0Zhenfa Li1Ligang Song2Weimin Xie3Xianghao Gong4Dongliang He5Xin Zhang6Department of Neurosurgery, Affiliated Hengyang Hospital, Southern Medical University (Hengyang Central Hospital)Department of Vascular Surgery, Affiliated Hengyang Hospital, Southern Medical University (Hengyang Central Hospital)Department of Neurointervention, Affiliated Tiantan Hospital, Capital Medical UniversityDepartment of Gynecology, Affiliated Hengyang Hospital, Southern Medical University (Hengyang Central Hospital)Department of Science and Education, Affiliated Hengyang Hospital, Southern Medical University (Hengyang Central Hospital)Department of Nutrition, Affiliated Hengyang Hospital, Southern Medical University (Hengyang Central Hospital)Department of Neurosurgery, Zhujiang Hospital, Southern Medical UniversityAbstract Background To evaluate the medium-and long-term effect of intravascular interventional therapy for symptomatic severe basilar artery stenosis supported by multimodal imaging. Method After strict screening of 67 patients with symptomatic severe basilar artery stenosis (70–99%) with atherosclerotic stenosis, 67 patients with symptomatic recurrence after intensive drug treatment were treated with intravascular balloon dilatation and Enterprise stent implantation. Any stroke or death within 30 days after operation and any stroke and restenosis during medium-and long-term follow-up were recorded. Results ①The mean age of 67 patients (67lesions) was 57 ± 8 years old, and the technical success rate was 100%; ②Preoperative angiography showed that the collateral circulation was poor, and TICI was 1-2a while postoperative angiography showed that TICI was significantly improved to 2b-3; ③The average preoperative stenosis rate was 82 ± 9%, and the postoperative stenosis rate was reduced to 17 ± 10%; ④Before surgery, abnormal perfusion was found in the posterior circulation CTP; After the postoperative re-examination, the posterior circulation of CTP perfusion was significantly improved; ⑤Postoperative symptoms and neurological conditions improved significantly; ⑥Complications of perforating branch event occurred in 1 case after operation, and symptoms were relieved after more than 1 month of medication treatment, and mild neurological dysfunction remained. 1 case developed subacute thrombosis in the stent, which improved after active intra-arterial thrombolysis, and there was no residual neurological dysfunction; and 1 case of micro-guide wire being trapped by the distal vasospasm. ⑦67 patients were followed up by telephone, WeChat or imaging for 36–66 months. Conclusions In summary intravascular balloon dilation + Enterprise stent implantation is safe and effective for the treatment of symptomatic severe atherosclerotic stenosis of the basilar artery, with high technical success rate, low perioperative complications, and good mid-term and long-term effects.http://link.springer.com/article/10.1186/s12883-020-01863-5Basilar arteryStenosisAtherosclerosisStent implantationAngioplasty |
| spellingShingle | Yuanzhi Li Zhenfa Li Ligang Song Weimin Xie Xianghao Gong Dongliang He Xin Zhang Medium- and long-term effects of endovascular treatments for severely stenotic basilar arteries supported by multimodal imaging BMC Neurology Basilar artery Stenosis Atherosclerosis Stent implantation Angioplasty |
| title | Medium- and long-term effects of endovascular treatments for severely stenotic basilar arteries supported by multimodal imaging |
| title_full | Medium- and long-term effects of endovascular treatments for severely stenotic basilar arteries supported by multimodal imaging |
| title_fullStr | Medium- and long-term effects of endovascular treatments for severely stenotic basilar arteries supported by multimodal imaging |
| title_full_unstemmed | Medium- and long-term effects of endovascular treatments for severely stenotic basilar arteries supported by multimodal imaging |
| title_short | Medium- and long-term effects of endovascular treatments for severely stenotic basilar arteries supported by multimodal imaging |
| title_sort | medium and long term effects of endovascular treatments for severely stenotic basilar arteries supported by multimodal imaging |
| topic | Basilar artery Stenosis Atherosclerosis Stent implantation Angioplasty |
| url | http://link.springer.com/article/10.1186/s12883-020-01863-5 |
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