Advanced Urea Precursors Driven NiCo<sub>2</sub>O<sub>4</sub> Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications
The electrochemical performance of NiCo<sub>2</sub>O<sub>4</sub> with urea precursors was evaluated in order to develop a non-enzymatic urea sensor. In this study, NiCo<sub>2</sub>O<sub>4</sub> nanostructures were synthesized hydrothermally at differen...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/13/4/444 |
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| author | Sanjha Mangrio Aneela Tahira Abdul Sattar Chang Ihsan Ali Mahar Mehnaz Markhand Aqeel Ahmed Shah Shymaa S. Medany Ayman Nafady Elmuez A. Dawi Lama M. A. Saleem E. M. Mustafa Brigitte Vigolo Zafar Hussain Ibupoto |
| author_facet | Sanjha Mangrio Aneela Tahira Abdul Sattar Chang Ihsan Ali Mahar Mehnaz Markhand Aqeel Ahmed Shah Shymaa S. Medany Ayman Nafady Elmuez A. Dawi Lama M. A. Saleem E. M. Mustafa Brigitte Vigolo Zafar Hussain Ibupoto |
| author_sort | Sanjha Mangrio |
| collection | DOAJ |
| description | The electrochemical performance of NiCo<sub>2</sub>O<sub>4</sub> with urea precursors was evaluated in order to develop a non-enzymatic urea sensor. In this study, NiCo<sub>2</sub>O<sub>4</sub> nanostructures were synthesized hydrothermally at different concentrations of urea and characterized using scanning electron microscopy and X-ray diffraction. Nanostructures of NiCo<sub>2</sub>O<sub>4</sub> exhibit a nanorod-like morphology and a cubic phase crystal structure. Urea can be detected with high sensitivity through NiCo<sub>2</sub>O<sub>4</sub> nanostructures driven by urea precursors under alkaline conditions. A low limit of detection of 0.05 and an analytical range of 0.1 mM to 10 mM urea are provided. The concentration of 006 mM was determined by cyclic voltammetry. Chronoamperometry was used to determine the linear range in the range of 0.1 mM to 8 mM. Several analytical parameters were assessed, including selectivity, stability, and repeatability. NiCo<sub>2</sub>O<sub>4</sub> nanostructures can also be used to detect urea in various biological samples in a practical manner. |
| first_indexed | 2024-03-11T05:11:43Z |
| format | Article |
| id | doaj.art-1bafe7577ad5436d9b3a783bc1affba7 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-11T05:11:43Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-1bafe7577ad5436d9b3a783bc1affba72023-11-17T18:30:46ZengMDPI AGBiosensors2079-63742023-03-0113444410.3390/bios13040444Advanced Urea Precursors Driven NiCo<sub>2</sub>O<sub>4</sub> Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample ApplicationsSanjha Mangrio0Aneela Tahira1Abdul Sattar Chang2Ihsan Ali Mahar3Mehnaz Markhand4Aqeel Ahmed Shah5Shymaa S. Medany6Ayman Nafady7Elmuez A. Dawi8Lama M. A. Saleem9E. M. Mustafa10Brigitte Vigolo11Zafar Hussain Ibupoto12Dr. M.A. Kazi Institute of Chemistry, University of Sindh, Jamshoro 76080, PakistanInstitute of Chemistry, Shah Abdul Latif University, Khairpur Mirs 66111, PakistanDr. M.A. Kazi Institute of Chemistry, University of Sindh, Jamshoro 76080, PakistanDr. M.A. Kazi Institute of Chemistry, University of Sindh, Jamshoro 76080, PakistanDr. M.A. Kazi Institute of Chemistry, University of Sindh, Jamshoro 76080, PakistanDepartment of metalluargy and Materials, NED University of Engineering and Technology, Karachi 75270, PakistanDepartment of Chemistry, Faculty of Science, Cairo University, Giza 12613, EgyptDepartment of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi ArabiaNonlinear Dynamics Research Centre (NDRC), Ajman University, Ajman P.O. Box 346, United Arab EmiratesBiomolecular Science, Earth and Life Science, Amsterdam University, 1081 HV Amsterdam, The NetherlandsDepartment of Sciences and Technology, Linköping University, SE-601 74 Norrköping, SwedenThe Institut Jean Lamour (IJL), Université de Lorraine, CNRS, F-54000 Nancy, FranceDr. M.A. Kazi Institute of Chemistry, University of Sindh, Jamshoro 76080, PakistanThe electrochemical performance of NiCo<sub>2</sub>O<sub>4</sub> with urea precursors was evaluated in order to develop a non-enzymatic urea sensor. In this study, NiCo<sub>2</sub>O<sub>4</sub> nanostructures were synthesized hydrothermally at different concentrations of urea and characterized using scanning electron microscopy and X-ray diffraction. Nanostructures of NiCo<sub>2</sub>O<sub>4</sub> exhibit a nanorod-like morphology and a cubic phase crystal structure. Urea can be detected with high sensitivity through NiCo<sub>2</sub>O<sub>4</sub> nanostructures driven by urea precursors under alkaline conditions. A low limit of detection of 0.05 and an analytical range of 0.1 mM to 10 mM urea are provided. The concentration of 006 mM was determined by cyclic voltammetry. Chronoamperometry was used to determine the linear range in the range of 0.1 mM to 8 mM. Several analytical parameters were assessed, including selectivity, stability, and repeatability. NiCo<sub>2</sub>O<sub>4</sub> nanostructures can also be used to detect urea in various biological samples in a practical manner.https://www.mdpi.com/2079-6374/13/4/444urea precursorsNiCo<sub>2</sub>O<sub>4</sub> nanostructuresnon-enzymatic sensoralkaline conditions |
| spellingShingle | Sanjha Mangrio Aneela Tahira Abdul Sattar Chang Ihsan Ali Mahar Mehnaz Markhand Aqeel Ahmed Shah Shymaa S. Medany Ayman Nafady Elmuez A. Dawi Lama M. A. Saleem E. M. Mustafa Brigitte Vigolo Zafar Hussain Ibupoto Advanced Urea Precursors Driven NiCo<sub>2</sub>O<sub>4</sub> Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications Biosensors urea precursors NiCo<sub>2</sub>O<sub>4</sub> nanostructures non-enzymatic sensor alkaline conditions |
| title | Advanced Urea Precursors Driven NiCo<sub>2</sub>O<sub>4</sub> Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications |
| title_full | Advanced Urea Precursors Driven NiCo<sub>2</sub>O<sub>4</sub> Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications |
| title_fullStr | Advanced Urea Precursors Driven NiCo<sub>2</sub>O<sub>4</sub> Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications |
| title_full_unstemmed | Advanced Urea Precursors Driven NiCo<sub>2</sub>O<sub>4</sub> Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications |
| title_short | Advanced Urea Precursors Driven NiCo<sub>2</sub>O<sub>4</sub> Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications |
| title_sort | advanced urea precursors driven nico sub 2 sub o sub 4 sub nanostructures based non enzymatic urea sensor for milk and urine real sample applications |
| topic | urea precursors NiCo<sub>2</sub>O<sub>4</sub> nanostructures non-enzymatic sensor alkaline conditions |
| url | https://www.mdpi.com/2079-6374/13/4/444 |
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