Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management

Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management

The innovative advances in transforming clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR/Cas9) into different variants have taken the art of genome-editing specificity to new heights. Allosteric modulation of Cas9-targeting specificity by sgRNA sequence alterati...

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Bibliographic Details
Main Authors: Khaled S. Allemailem, Saleh A. Almatroodi, Ahmad Almatroudi, Faris Alrumaihi, Waleed Al Abdulmonem, Wafa Abdullah I. Al-Megrin, Adel Nasser Aljamaan, Arshad Husain Rahmani, Amjad Ali Khan
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
CRISPR/Cas9
Cas9 variants
gene expression
cancer therapy
tumor microenvironment
nanotechnology
Online Access:https://www.mdpi.com/1422-0067/24/8/7052

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