Social isolation and loneliness with risk of cardiometabolic multimorbidity: A prospective cohort study from UK Biobank
Summary: The pandemic of the coronavirus disease 2019 resulted in an increased prevalence of social isolation and loneliness. Cox proportional hazards regression was used to test the association between social isolation/loneliness, multiple cardiometabolic diseases (CMDs) and cardiometabolic multimo...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224003304 |
| _version_ | 1797267579421589504 |
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| author | Zhilin Xiao Jing Li Yi Luo Liu Yang Guogang Zhang Xunjie Cheng Yongping Bai |
| author_facet | Zhilin Xiao Jing Li Yi Luo Liu Yang Guogang Zhang Xunjie Cheng Yongping Bai |
| author_sort | Zhilin Xiao |
| collection | DOAJ |
| description | Summary: The pandemic of the coronavirus disease 2019 resulted in an increased prevalence of social isolation and loneliness. Cox proportional hazards regression was used to test the association between social isolation/loneliness, multiple cardiometabolic diseases (CMDs) and cardiometabolic multimorbidity (CMM). In the multivariable adjusted models, compared with the least isolated, the most isolated had independently associated with CMD (HR 1.07, 95% CI 1.03 to 1.11) and CMM (HR 1.24, 95% CI 1.12 to 1.36) in stage I, and CMM in stage II (HR 1.14, 95% CI 1.05 to 1.23). Compared with those with the least loneliness, those who with most loneliness had about 20% increased risk of CMD and 29% increased risk of CMM in stage I. Those with the most loneliness were also significantly associated with increased CMM risk (HR 1.30, 95% CI 1.19 to 1.42) in stage II. This study revealed the associations of social isolation/loneliness with CMD and CMM. |
| first_indexed | 2024-04-25T01:18:50Z |
| format | Article |
| id | doaj.art-1bb54bbb87ff45d2b8ac9d8d3c7d1c65 |
| institution | Directory Open Access Journal |
| issn | 2589-0042 |
| language | English |
| last_indexed | 2024-04-25T01:18:50Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj.art-1bb54bbb87ff45d2b8ac9d8d3c7d1c652024-03-09T09:29:19ZengElsevieriScience2589-00422024-04-01274109109Social isolation and loneliness with risk of cardiometabolic multimorbidity: A prospective cohort study from UK BiobankZhilin Xiao0Jing Li1Yi Luo2Liu Yang3Guogang Zhang4Xunjie Cheng5Yongping Bai6Department of Geriatric Disease, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Changsha, ChinaDepartment of Geriatric Disease, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Changsha, China; Department of Cardiology, The Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Geriatric Disease, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Changsha, ChinaDepartment of Geriatric Disease, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Changsha, ChinaDepartment of Cardiology, The Third Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Geriatric Disease, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Changsha, China; Corresponding authorDepartment of Geriatric Disease, Center of Coronary Circulation, Xiangya Hospital, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Changsha, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China; Corresponding authorSummary: The pandemic of the coronavirus disease 2019 resulted in an increased prevalence of social isolation and loneliness. Cox proportional hazards regression was used to test the association between social isolation/loneliness, multiple cardiometabolic diseases (CMDs) and cardiometabolic multimorbidity (CMM). In the multivariable adjusted models, compared with the least isolated, the most isolated had independently associated with CMD (HR 1.07, 95% CI 1.03 to 1.11) and CMM (HR 1.24, 95% CI 1.12 to 1.36) in stage I, and CMM in stage II (HR 1.14, 95% CI 1.05 to 1.23). Compared with those with the least loneliness, those who with most loneliness had about 20% increased risk of CMD and 29% increased risk of CMM in stage I. Those with the most loneliness were also significantly associated with increased CMM risk (HR 1.30, 95% CI 1.19 to 1.42) in stage II. This study revealed the associations of social isolation/loneliness with CMD and CMM.http://www.sciencedirect.com/science/article/pii/S2589004224003304Cardiovascular medicineSocial sciences |
| spellingShingle | Zhilin Xiao Jing Li Yi Luo Liu Yang Guogang Zhang Xunjie Cheng Yongping Bai Social isolation and loneliness with risk of cardiometabolic multimorbidity: A prospective cohort study from UK Biobank iScience Cardiovascular medicine Social sciences |
| title | Social isolation and loneliness with risk of cardiometabolic multimorbidity: A prospective cohort study from UK Biobank |
| title_full | Social isolation and loneliness with risk of cardiometabolic multimorbidity: A prospective cohort study from UK Biobank |
| title_fullStr | Social isolation and loneliness with risk of cardiometabolic multimorbidity: A prospective cohort study from UK Biobank |
| title_full_unstemmed | Social isolation and loneliness with risk of cardiometabolic multimorbidity: A prospective cohort study from UK Biobank |
| title_short | Social isolation and loneliness with risk of cardiometabolic multimorbidity: A prospective cohort study from UK Biobank |
| title_sort | social isolation and loneliness with risk of cardiometabolic multimorbidity a prospective cohort study from uk biobank |
| topic | Cardiovascular medicine Social sciences |
| url | http://www.sciencedirect.com/science/article/pii/S2589004224003304 |
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