Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age
Oscar MP JolobeManchester Medical Society, Manchester, United KingdomThe assertion that aging is associated with a decreasing concentration of thyrotropin-stimulating hormone (TSH) in healthy elderly humans1 appears to be at odds with the observation that "TSH distribution shifts towards hi...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2012-08-01
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| Series: | Clinical Interventions in Aging |
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| Online Access: | https://www.dovepress.com/upper-limit-of-the-normal-range-for-thyrotropin-stimulating-hormone-is-peer-reviewed-article-CIA |
| _version_ | 1818855630595686400 |
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| author | Jolobe OM |
| author_facet | Jolobe OM |
| author_sort | Jolobe OM |
| collection | DOAJ |
| description | Oscar MP JolobeManchester Medical Society, Manchester, United KingdomThe assertion that aging is associated with a decreasing concentration of thyrotropin-stimulating hormone (TSH) in healthy elderly humans1 appears to be at odds with the observation that "TSH distribution shifts towards higher concentrations with age."2 The latter conclusion was based on a study that analyzed the age-specific distribution of serum TSH in 14,376 disease-free subjects with negative thyroid antibody tests. In that study, the percentage of TSH measurements in the 2.5–4.5 mIU/L range progressively increased with age from approximately 6.5% in the 20–29-year age group to 23.9% in the 80 years and older age group. Likewise, the percentage of TSH measurements in the .4.5 mIU/L category progressively increased from 2.0% in the 20–29-year age group to 12% in the 80 years and older age group.View original paper by Bensenor and colleagues.Corrigendum for this letter has been published |
| first_indexed | 2024-12-19T08:11:40Z |
| format | Article |
| id | doaj.art-1bb5efb74e044186b11454282b69ad43 |
| institution | Directory Open Access Journal |
| issn | 1178-1998 |
| language | English |
| last_indexed | 2024-12-19T08:11:40Z |
| publishDate | 2012-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Interventions in Aging |
| spelling | doaj.art-1bb5efb74e044186b11454282b69ad432022-12-21T20:29:36ZengDove Medical PressClinical Interventions in Aging1178-19982012-08-01Volume 729930110585Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing ageJolobe OMOscar MP JolobeManchester Medical Society, Manchester, United KingdomThe assertion that aging is associated with a decreasing concentration of thyrotropin-stimulating hormone (TSH) in healthy elderly humans1 appears to be at odds with the observation that "TSH distribution shifts towards higher concentrations with age."2 The latter conclusion was based on a study that analyzed the age-specific distribution of serum TSH in 14,376 disease-free subjects with negative thyroid antibody tests. In that study, the percentage of TSH measurements in the 2.5–4.5 mIU/L range progressively increased with age from approximately 6.5% in the 20–29-year age group to 23.9% in the 80 years and older age group. Likewise, the percentage of TSH measurements in the .4.5 mIU/L category progressively increased from 2.0% in the 20–29-year age group to 12% in the 80 years and older age group.View original paper by Bensenor and colleagues.Corrigendum for this letter has been published https://www.dovepress.com/upper-limit-of-the-normal-range-for-thyrotropin-stimulating-hormone-is-peer-reviewed-article-CIAUpper;limitTSHincreasingage |
| spellingShingle | Jolobe OM Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age Clinical Interventions in Aging Upper;limit TSH increasing age |
| title | Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age |
| title_full | Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age |
| title_fullStr | Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age |
| title_full_unstemmed | Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age |
| title_short | Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age |
| title_sort | upper limit of the normal range for thyrotropin stimulating hormone is higher with increasing age |
| topic | Upper;limit TSH increasing age |
| url | https://www.dovepress.com/upper-limit-of-the-normal-range-for-thyrotropin-stimulating-hormone-is-peer-reviewed-article-CIA |
| work_keys_str_mv | AT jolobeom upperlimitofthenormalrangeforthyrotropinstimulatinghormoneishigherwithincreasingage |