Neuromyelitis Optica with NMO-IgG/ Anti-AQP4 Antibody Positive: First Case Reported from Uttarakhand India
Neuromyelitis optica (also known as Devic’s disease) is an idiopathic, severe, demyelinating disease of the central nervous system that preferentially affects the optic nerve and spinal cord. The presence of a highly specific serum autoantibody marker (NMO-IgG) further differentiates neuromyelitis...
| Main Authors: | , |
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| Format: | Article |
| Jezik: | English |
| Izdano: |
JCDR Research and Publications Private Limited
2014-07-01
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| Serija: | Journal of Clinical and Diagnostic Research |
| Teme: | |
| Online dostop: | https://jcdr.net/articles/PDF/4625/8577_CE(Ra)_F(Sh)_PF1(PAK)_PFA(P).pdf |
| Izvleček: | Neuromyelitis optica (also known as Devic’s disease) is an idiopathic, severe, demyelinating disease of the central nervous system that
preferentially affects the optic nerve and spinal cord. The presence of a highly specific serum autoantibody marker (NMO-IgG) further differentiates neuromyelitis optica from multiple sclerosis and has helped to define a neuromyelitis optica spectrum of disorders. We present
a case of 37-year-old man who has initially presented with transverse myelitis from which he recovered partially after treatment but later
presented with bilateral optic neuritis. MRI brain revealed hyperintensity in bilateral optic nerves, periventricular area and also in the thalamic
region. Diagnosis was confirmed by positive NMO – IgG/anti-AQP4 antibody. |
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| ISSN: | 2249-782X 0973-709X |