When aging reaches CD4+ T-cells: phenotypic and functional changes

When aging reaches CD4+ T-cells: phenotypic and functional changes

Beyond midlife, the immune system shows aging features and its defensive capability becomes impaired, by a process known as immunosenescence that involves many changes in the innate and adaptive responses. Innate immunity seems to be better preserved globally, while the adaptive immune response exhi...

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Bibliographic Details
Main Authors: Marco Antonio Moro-García, Rebeca eAlonso-Arias, Carlos eLopez-Larrea
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Immunology
Subjects:
Inflammation
immunosenescence
T-cells
IL-15
CMV
NKRs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00107/full

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