Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents

Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents

Proteolytic targeting chimaeras (PROTACs) have been developed as an effective technology for targeted protein degradation. PROTACs are heterobifunctional molecules that can trigger the polyubiquitination of proteins of interest (POIs) by recruiting the ubiquitin-proteasome system, thereby inhibiting...

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Bibliographic Details
Main Authors: Chao Wang, Yujing Zhang, Lingyu Shi, Shanbo Yang, Jing Chang, Yingjie Zhong, Qian Li, Dongming Xing
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
PROTACs
IAP
SNIPERs
degradation
promising treatment
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2022.2074414

Internet

https://www.tandfonline.com/doi/10.1080/14756366.2022.2074414

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