Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro

Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro

Non-alcoholic fatty liver disease (NAFLD) is considered to be the hepatic manifestation of the metabolic syndrome. The bone morphogenetic protein-8B (BMP8B) has been shown to be expressed in brown adipose tissues and the hypothalamus and to affect thermogenesis and susceptibility to diet-induced obe...

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Bibliographic Details
Main Authors: Abdo Mahli, Tatjana Seitz, Tobias Beckröge, Kim Freese, Wolfgang Erwin Thasler, Matthias Benkert, Peter Dietrich, Ralf Weiskirchen, Anja Bosserhoff, Claus Hellerbrand
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
BMP8B
steatosis
inflammation
NAFLD
non-alcoholic fatty liver disease
Online Access:https://www.mdpi.com/2073-4409/8/5/457

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