DUX4 expression activates JNK and p38 MAP kinases in myoblasts

DUX4 expression activates JNK and p38 MAP kinases in myoblasts

Bibliographic Details
Main Authors:	Christopher M. Brennan, Abby S. Hill, Michael St. Andre, Xianfeng Li, Vijaya Madeti, Susanne Breitkopf, Seth Garren, Liang Xue, Tamara Gilbert, Angela Hadjipanayis, Mara Monetti, Charles P. Emerson, Robert Moccia, Jane Owens, Nicolas Christoforou
Format:	Article
Language:	English
Published:	The Company of Biologists 2022-11-01
Series:	Disease Models & Mechanisms
Subjects:	map kinase signaling muscular dystrophy phosphoproteomics
Online Access:	http://dmm.biologists.org/content/15/11/dmm049516

Similar Items

Functional domains of the FSHD-associated DUX4 protein
by: Hiroaki Mitsuhashi, et al.
Published: (2018-04-01)

Influence of <i>DUX4</i> Expression in Facioscapulohumeral Muscular Dystrophy and Possible Treatments
by: Elisa Duranti, et al.
Published: (2023-05-01)

Pharyngeal pathology in a mouse model of oculopharyngeal muscular dystrophy is associated with impaired basal autophagy in myoblasts
by: Yu Zhang, et al.
Published: (2022-10-01)

Analysis of DUX4 Expression in Bone Marrow and Re-Discussion of DUX4 Function in the Health and Disease
by: Ceren HANGUL, et al.
Published: (2022-09-01)

p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy
by: Darko Bosnakovski, et al.
Published: (2017-10-01)

Molecular and Phenotypic Changes in FLExDUX4 Mice
by: Kelly Murphy, et al.
Published: (2023-06-01)

A FRAMEWORK FOR PSYCHOLOGICAL MANAGEMENT OF INDIVIDUALS WITH MUSCULAR DYSTROPHY /
by: Elna Herawati Che Ismail, author 654886, et al.
Published: (2022)

A FRAMEWORK FOR PSYCHOLOGICAL MANAGEMENT OF INDIVIDUALS WITH MUSCULAR DYSTROPHY /
by: Elna Herawati Che Ismail, author 654886, et al.
Published: (2022)

Antagonism Between DUX4 and DUX4c Highlights a Pathomechanism Operating Through β-Catenin in Facioscapulohumeral Muscular Dystrophy
by: Massimo Ganassi, et al.
Published: (2022-09-01)

Pathomechanisms and biomarkers in facioscapulohumeral muscular dystrophy: roles of DUX4 and PAX7
by: Christopher R S Banerji, et al.
Published: (2021-08-01)

Persistent Fibroadipogenic Progenitor Expansion Following Transient DUX4 Expression Provokes a Profibrotic State in a Mouse Model for FSHD
by: Darko Bosnakovski, et al.
Published: (2022-02-01)

A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy
by: Qing Feng, et al.
Published: (2015-01-01)

Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4
by: Sachiko Homma, et al.
Published: (2016-12-01)

Sporadic DUX4 expression in FSHD myocytes is associated with incomplete repression by the PRC2 complex and gain of H3K9 acetylation on the contracted D4Z4 allele
by: Premi Haynes, et al.
Published: (2018-08-01)

Duchenne muscular dystrophy: an historical treatment review
by: Lineu Cesar Werneck, et al.

Meeting report: the 2020 FSHD International Research Congress
by: Michael Kyba, et al.
Published: (2020-12-01)

TAK1 inhibition improves myoblast differentiation and alleviates fibrosis in a mouse model of Duchenne muscular dystrophy
by: Dengqiu Xu, et al.
Published: (2021-02-01)

An in silico FSHD muscle fiber for modeling DUX4 dynamics and predicting the impact of therapy
by: Matthew V Cowley, et al.
Published: (2023-05-01)

Integrative Cell Type-Specific Multi-Omics Approaches Reveal Impaired Programs of Glial Cell Differentiation in Mouse Culture Models of DM1
by: Anchel González-Barriga, et al.
Published: (2021-05-01)

Muscular Dystrophy /
by: Naff, Clay Farris, editor 192865, et al.
Published: (2012)

A rare case of dystrophinopathy: Duchenne muscular dystrophy–Becker muscular dystrophy intermediate complex
by: Rachna Gulati, et al.
Published: (2022-01-01)

The association of hand grip strength with functional measures in non-ambulatory children with Duchenne muscular dystrophy
by: Numan Bulut, et al.
Published: (2019-12-01)

Analysis of DMD translocations
by: Cockburn, D, et al.
Published: (1991)

Proximity ligation assay to detect DUX4 protein in FSHD1 muscle: a pilot study
by: Mary Lou Beermann, et al.
Published: (2022-05-01)

P2X7 Receptor Antagonist Reduces Fibrosis and Inflammation in a Mouse Model of Alpha-Sarcoglycan Muscular Dystrophy
by: Lizzia Raffaghello, et al.
Published: (2022-01-01)

Duchenne muscular dystrophy: Genetic and clinical profile in the population of Rajasthan, India
by: Manisha Goyal, et al.
Published: (2021-01-01)

BET bromodomain inhibitors and agonists of the beta-2 adrenergic receptor identified in screens for compounds that inhibit DUX4 expression in FSHD muscle cells
by: Amy E. Campbell, et al.
Published: (2017-09-01)

Adenine base editing of the DUX4 polyadenylation signal for targeted genetic therapy in facioscapulohumeral muscular dystrophy
by: Darina Šikrová, et al.
Published: (2021-09-01)

Targeted epigenetic repression by CRISPR/dSaCas9 suppresses pathogenic DUX4-fl expression in FSHD
by: Charis L. Himeda, et al.
Published: (2021-03-01)

Structural analysis and modeling comparison of primates Dystrophin /
by: Faeze Sadat Mohajer, 1987-, et al.
Published: (2013)

Structural analysis and modeling comparison of primates Dystrophin [electronic resource] /
by: Faeze Sadat Mohajer, 1987-
Published: (2013)

Rather mild phenotype in a patient with homozygous null mutations in the a-sarcoglycan gene
by: M Gasperini, et al.
Published: (2006-02-01)

Absence of the dystrophin protein in Duchenne muscular dystrophy: effects on transcriptome, proteome and microRNA secretome
by: van Westering, T
Published: (2018)

Errata: Measuring Disease Severity in Duchenne and Becker Muscular Dystrophy
by: Melinda F. Davis, et al.
Published: (2011-05-01)

A novel biomarker of fibrofatty replacement in dystrophinopathies identified by integrating transcriptome, magnetic resonance imaging, and pathology data
by: Zhihao Xie, et al.
Published: (2024-02-01)

Histone Deacetylases: Molecular Mechanisms and Therapeutic Implications for Muscular Dystrophies
by: Martina Sandonà, et al.
Published: (2023-02-01)

Assessment of Weighted Gene Co-Expression Network Analysis to Explore Key Pathways and Novel Biomarkers in Muscular Dystrophy
by: Xu X, et al.
Published: (2021-04-01)

Molecular Diagnosis of Duchenne/Becker Muscular Dystrophy: Analysis of Exons Deletion and Carrier Detection
by: Mohammad Taghi Akbari, et al.
Published: (2010-01-01)

On Tiptoes
by: Carol Whitfield, et al.
Published: (2009-03-01)

Comprehensive genetic characteristics of dystrophinopathies in China
by: Peipei Ma, et al.
Published: (2018-07-01)