Identification of a novel likely pathogenic TPM1 variant linked to hypertrophic cardiomyopathy in a family with sudden cardiac death

Identification of a novel likely pathogenic TPM1 variant linked to hypertrophic cardiomyopathy in a family with sudden cardiac death

Abstract Aims Hypertrophic cardiomyopathy (HCM) is an autosomal dominant genetic cardiac disorder characterized by unexplained left ventricular hypertrophy. It can cause a wide spectrum of clinical manifestations, ranging from asymptomatic to heart failure and sudden cardiac death (SCD). Approximate...

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Bibliographic Details
Main Authors: Amir Azimi, Mahdieh Soveizi, Alireza Salmanipour, Mohammadhossein Mozafarybazargany, Amir Ghaffari Jolfayi, Majid Maleki, Samira Kalayinia
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:ESC Heart Failure
Subjects:
genetic
hypertrophic cardiomyopathy
tropomyosin
variant
whole‐exome sequencing
Online Access:https://doi.org/10.1002/ehf2.14906

Internet

https://doi.org/10.1002/ehf2.14906

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