The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney Disease
Artemisinin (ARS) and its derivatives (ARSs) are recommended as the first-line antimalarial drugs for the treatment of malaria. Besides antimalarial function, its potent anti-inflammatory and immunoregulatory properties, as well as the ability to regulate oxidative stress have brought them to a prom...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-03-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2020.00380/full |
| _version_ | 1818140855113875456 |
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| author | Ming Xia Di Liu Yu Liu Hong Liu |
| author_facet | Ming Xia Di Liu Yu Liu Hong Liu |
| author_sort | Ming Xia |
| collection | DOAJ |
| description | Artemisinin (ARS) and its derivatives (ARSs) are recommended as the first-line antimalarial drugs for the treatment of malaria. Besides antimalarial function, its potent anti-inflammatory and immunoregulatory properties, as well as the ability to regulate oxidative stress have brought them to a prominent position. As researchers around the world are continually exploring the unknown biological activities of ARS derivatives, experimental studies have shown much progress in renal therapy. This review aims to give a brief overview of the current research on ARSs applications for kidney treatment with the evaluation of therapeutic properties and potential molecular mechanisms. |
| first_indexed | 2024-12-11T10:50:37Z |
| format | Article |
| id | doaj.art-1bbf3e447f6749dabf9ee93bb2d08f61 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-12-11T10:50:37Z |
| publishDate | 2020-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-1bbf3e447f6749dabf9ee93bb2d08f612022-12-22T01:10:19ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122020-03-011110.3389/fphar.2020.00380495138The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney DiseaseMing XiaDi LiuYu LiuHong LiuArtemisinin (ARS) and its derivatives (ARSs) are recommended as the first-line antimalarial drugs for the treatment of malaria. Besides antimalarial function, its potent anti-inflammatory and immunoregulatory properties, as well as the ability to regulate oxidative stress have brought them to a prominent position. As researchers around the world are continually exploring the unknown biological activities of ARS derivatives, experimental studies have shown much progress in renal therapy. This review aims to give a brief overview of the current research on ARSs applications for kidney treatment with the evaluation of therapeutic properties and potential molecular mechanisms.https://www.frontiersin.org/article/10.3389/fphar.2020.00380/fullartemisinin derivatives (artemisinins)kidney diseaseinflammationimmunityoxidative stress |
| spellingShingle | Ming Xia Di Liu Yu Liu Hong Liu The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney Disease Frontiers in Pharmacology artemisinin derivatives (artemisinins) kidney disease inflammation immunity oxidative stress |
| title | The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney Disease |
| title_full | The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney Disease |
| title_fullStr | The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney Disease |
| title_full_unstemmed | The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney Disease |
| title_short | The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney Disease |
| title_sort | therapeutic effect of artemisinin and its derivatives in kidney disease |
| topic | artemisinin derivatives (artemisinins) kidney disease inflammation immunity oxidative stress |
| url | https://www.frontiersin.org/article/10.3389/fphar.2020.00380/full |
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