Hodgkin Lymphoma Mimicking Osteomyelitis

Hodgkin lymphoma with symptomatic osseous involvement can have a similar presentation to osteomyelitis. Common findings in symptoms, laboratory workup, and imaging can make it very difficult to distinguish between the two diseases. Excisional biopsy should be pursued if fine-needle biopsy is equivoc...

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Main Authors: Aneela Majeed, Onyee Chan, Onyemaechi Okolo, Volodymyr Shponka, Anca Georgescu, Daniel Persky
Format: Article
Language:English
Published: Karger Publishers 2017-06-01
Series:Case Reports in Oncology
Subjects:
Online Access:http://www.karger.com/Article/FullText/474938
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author Aneela Majeed
Onyee Chan
Onyemaechi Okolo
Volodymyr Shponka
Anca Georgescu
Daniel Persky
author_facet Aneela Majeed
Onyee Chan
Onyemaechi Okolo
Volodymyr Shponka
Anca Georgescu
Daniel Persky
author_sort Aneela Majeed
collection DOAJ
description Hodgkin lymphoma with symptomatic osseous involvement can have a similar presentation to osteomyelitis. Common findings in symptoms, laboratory workup, and imaging can make it very difficult to distinguish between the two diseases. Excisional biopsy should be pursued if fine-needle biopsy is equivocal and suspicion of lymphoma is high. We report a case of a 40-year-old man who presented with a history of marine animal sting on his neck and later developed erythema in the area, chest pain, constitutional symptoms, adenopathy, and imaging classic for sternal osteomyelitis. Fortunately, initial biopsy prompted the possibility of lymphoma, and further workup was initiated, which confirmed Hodgkin lymphoma. This case is a good reminder that malignancies and infections can share many common features, and keeping a broad differential diagnosis can be lifesaving. Proper staging and risk stratification of Hodgkin lymphoma help determine the optimal treatment.
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spelling doaj.art-1bc04ce384ce48fda03e0914cb24bda62022-12-21T17:46:03ZengKarger PublishersCase Reports in Oncology1662-65752017-06-0110254254710.1159/000474938474938Hodgkin Lymphoma Mimicking OsteomyelitisAneela MajeedOnyee ChanOnyemaechi OkoloVolodymyr ShponkaAnca GeorgescuDaniel PerskyHodgkin lymphoma with symptomatic osseous involvement can have a similar presentation to osteomyelitis. Common findings in symptoms, laboratory workup, and imaging can make it very difficult to distinguish between the two diseases. Excisional biopsy should be pursued if fine-needle biopsy is equivocal and suspicion of lymphoma is high. We report a case of a 40-year-old man who presented with a history of marine animal sting on his neck and later developed erythema in the area, chest pain, constitutional symptoms, adenopathy, and imaging classic for sternal osteomyelitis. Fortunately, initial biopsy prompted the possibility of lymphoma, and further workup was initiated, which confirmed Hodgkin lymphoma. This case is a good reminder that malignancies and infections can share many common features, and keeping a broad differential diagnosis can be lifesaving. Proper staging and risk stratification of Hodgkin lymphoma help determine the optimal treatment.http://www.karger.com/Article/FullText/474938Hodgkin lymphomaLymphomaOsteomyelitisOsseous Hodgkin lymphoma
spellingShingle Aneela Majeed
Onyee Chan
Onyemaechi Okolo
Volodymyr Shponka
Anca Georgescu
Daniel Persky
Hodgkin Lymphoma Mimicking Osteomyelitis
Case Reports in Oncology
Hodgkin lymphoma
Lymphoma
Osteomyelitis
Osseous Hodgkin lymphoma
title Hodgkin Lymphoma Mimicking Osteomyelitis
title_full Hodgkin Lymphoma Mimicking Osteomyelitis
title_fullStr Hodgkin Lymphoma Mimicking Osteomyelitis
title_full_unstemmed Hodgkin Lymphoma Mimicking Osteomyelitis
title_short Hodgkin Lymphoma Mimicking Osteomyelitis
title_sort hodgkin lymphoma mimicking osteomyelitis
topic Hodgkin lymphoma
Lymphoma
Osteomyelitis
Osseous Hodgkin lymphoma
url http://www.karger.com/Article/FullText/474938
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