ROLE OF HEPATITIS B AND HEPATITS C VIRUS COINFECTION IN TB DEVELOPMENT

Tuberculosis developed differently in each individual. The role of HIV in the disease development is widely known unlike the role of Hepatitis B and Hepatitis C infection. Therefore, this study is aimed at to describe the role of those co-infections in the TB development. The study employed observat...

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Main Authors: Pudji Lestari, Ivan Rahmatullah, Dwi Susanti
Format: Article
Language:English
Published: Universitas Airlangga 2017-08-01
Series:Folia Medica Indonesiana
Subjects:
Online Access:https://e-journal.unair.ac.id/FMI/article/view/5204
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author Pudji Lestari
Ivan Rahmatullah
Dwi Susanti
author_facet Pudji Lestari
Ivan Rahmatullah
Dwi Susanti
author_sort Pudji Lestari
collection DOAJ
description Tuberculosis developed differently in each individual. The role of HIV in the disease development is widely known unlike the role of Hepatitis B and Hepatitis C infection. Therefore, this study is aimed at to describe the role of those co-infections in the TB development. The study employed observational – case control design with two groups, case and control group. Data collection include TB condition, whether latent or manifest, and history of Hepatitis B and Hepatitis C co-infection. The study successfully recruited the total of 32 respondents in each group. At the case group, the number of male and respondent is 19 and 13. Meanwhile, at the control group the number male respondent is 10 and the female respondent is 22. The study found that 20 and 12 respondents were positive Hepatitis B at the case and the control group. Chi-square test resulted significant different between two groups (P=0.0455 and a =0.05) with odd ratio p=0.479. Meanwhile, the study only tested one respondent with positive Hepatitis C at case group and one at control group. Comparison analysis found no significant different between groups (P=1 and a =0.05). This study reveals that TB patients are more likely to have history of Hepatitis B 2.7 times than those at the control group with the same infection but without TB development. Therefore, the possibility of Hepatitis B co-infection has role in the TB manifestation, but not for Hepatitis C co-infection.
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spelling doaj.art-1bc0df2ba9bb4cb3a12c74689580cd962022-12-22T00:48:49ZengUniversitas AirlanggaFolia Medica Indonesiana2355-83932599-056X2017-08-01521192310.20473/fmi.v52i1.52043226ROLE OF HEPATITIS B AND HEPATITS C VIRUS COINFECTION IN TB DEVELOPMENTPudji LestariIvan RahmatullahDwi SusantiTuberculosis developed differently in each individual. The role of HIV in the disease development is widely known unlike the role of Hepatitis B and Hepatitis C infection. Therefore, this study is aimed at to describe the role of those co-infections in the TB development. The study employed observational – case control design with two groups, case and control group. Data collection include TB condition, whether latent or manifest, and history of Hepatitis B and Hepatitis C co-infection. The study successfully recruited the total of 32 respondents in each group. At the case group, the number of male and respondent is 19 and 13. Meanwhile, at the control group the number male respondent is 10 and the female respondent is 22. The study found that 20 and 12 respondents were positive Hepatitis B at the case and the control group. Chi-square test resulted significant different between two groups (P=0.0455 and a =0.05) with odd ratio p=0.479. Meanwhile, the study only tested one respondent with positive Hepatitis C at case group and one at control group. Comparison analysis found no significant different between groups (P=1 and a =0.05). This study reveals that TB patients are more likely to have history of Hepatitis B 2.7 times than those at the control group with the same infection but without TB development. Therefore, the possibility of Hepatitis B co-infection has role in the TB manifestation, but not for Hepatitis C co-infection.https://e-journal.unair.ac.id/FMI/article/view/5204hepatitis B, hepatitis C, coinfection, tuberculosis
spellingShingle Pudji Lestari
Ivan Rahmatullah
Dwi Susanti
ROLE OF HEPATITIS B AND HEPATITS C VIRUS COINFECTION IN TB DEVELOPMENT
Folia Medica Indonesiana
hepatitis B, hepatitis C, coinfection, tuberculosis
title ROLE OF HEPATITIS B AND HEPATITS C VIRUS COINFECTION IN TB DEVELOPMENT
title_full ROLE OF HEPATITIS B AND HEPATITS C VIRUS COINFECTION IN TB DEVELOPMENT
title_fullStr ROLE OF HEPATITIS B AND HEPATITS C VIRUS COINFECTION IN TB DEVELOPMENT
title_full_unstemmed ROLE OF HEPATITIS B AND HEPATITS C VIRUS COINFECTION IN TB DEVELOPMENT
title_short ROLE OF HEPATITIS B AND HEPATITS C VIRUS COINFECTION IN TB DEVELOPMENT
title_sort role of hepatitis b and hepatits c virus coinfection in tb development
topic hepatitis B, hepatitis C, coinfection, tuberculosis
url https://e-journal.unair.ac.id/FMI/article/view/5204
work_keys_str_mv AT pudjilestari roleofhepatitisbandhepatitscviruscoinfectionintbdevelopment
AT ivanrahmatullah roleofhepatitisbandhepatitscviruscoinfectionintbdevelopment
AT dwisusanti roleofhepatitisbandhepatitscviruscoinfectionintbdevelopment