Quercetin-3-O-β-D-glucuronide inhibits mitochondria pathway-mediated platelet apoptosis via the phosphatidylinositol-3-kinase/AKT pathway in immunological bone marrow failure

Quercetin-3-O-β-D-glucuronide inhibits mitochondria pathway-mediated platelet apoptosis via the phosphatidylinositol-3-kinase/AKT pathway in immunological bone marrow failure

Objective: Quercetin-3-O-β-D-glucuronide (QG) can alleviate immunological bone marrow failure (BMF) by increasing platelet counts. However, the principal mechanism is less known. This study aimed at deciphering the possible underlying mechanism of QG that is indicated in thrombocytopenic purpura. Me...

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Bibliographic Details
Main Authors: Le-Min Xia, Ai-Ping Zhang, Qin Zheng, Jie Ding, Zhe Jin, Hai Yu, Wan-Hui Wong, He-Ping Yu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:World Journal of Traditional Chinese Medicine
Subjects:
apoptosis; mitochondrial pathway; phosphatidylinositol-3-kinase/akt; platelets; quercetin-3-o-β-d-glucuronide
Online Access:http://www.wjtcm.net/article.asp?issn=2311-8571;year=2022;volume=8;issue=1;spage=115;epage=122;aulast=Xia

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http://www.wjtcm.net/article.asp?issn=2311-8571;year=2022;volume=8;issue=1;spage=115;epage=122;aulast=Xia

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