The Use of Tissue Engineering to Fabricate Perfusable 3D Brain Microvessels in vitro

The Use of Tissue Engineering to Fabricate Perfusable 3D Brain Microvessels in vitro

Tissue engineering of the blood-brain barrier (BBB) in vitro has been rapidly expanding to address the challenges of mimicking the native structure and function of the BBB. Most of these models utilize 2D conventional microfluidic techniques. However, 3D microvascular models offer the potential to m...

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Bibliographic Details
Main Authors: Kalpani N. Udeni Galpayage Dona, Jonathan Franklin Hale, Tobi Salako, Akanksha Anandanatarajan, Kiet A. Tran, Brandon J. DeOre, Peter Adam Galie, Servio Heybert Ramirez, Allison Michelle Andrews
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Physiology
Subjects:
BBB
NVU
microfluidics
bioengineering
brain endothelial cells
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.715431/full

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