Prevalence of community-associated Methicillin-resistant Staphylococcus aureus (MRSA) isolates among women in Federal Capital Territory (Abuja), Nigeria
Background: Community-associated methicillin-resistant Staphylococcus aureus is increasingly reported. This study investigated its prevalence in urine of healthy women and resistance pattern to other antibiotics. Methods: Urine samples collected from healthy women volunteers in Federal Capital Terri...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2006-01-01
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| Series: | International Journal of Medicine and Health Development |
| Subjects: | |
| Online Access: | http://www.ijmhdev.com/article.asp?issn=2635-3695;year=2006;volume=11;issue=1;spage=47;epage=52;aulast=Onanuga;type=0 |
| _version_ | 1811220647588659200 |
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| author | Adebola Onanuga Busayo O Olayinka Avosuahi R Oyi Josiah A Onaolapo |
| author_facet | Adebola Onanuga Busayo O Olayinka Avosuahi R Oyi Josiah A Onaolapo |
| author_sort | Adebola Onanuga |
| collection | DOAJ |
| description | Background: Community-associated methicillin-resistant Staphylococcus aureus is increasingly reported. This study investigated its prevalence in urine of healthy women and resistance pattern to other antibiotics.
Methods: Urine samples collected from healthy women volunteers in Federal Capital Territory were cultured and screened for Staphylococcus aureus using standard microbiological procedures. The isolates were then subjected to antibiotic susceptibility testing using disc diffusion technique.
Results: A total of 60 (40%) Staphylococcus aureus isolates were isolated from 150 urine samples collected. The prevalence rate from married and single women were 41% and 38% respectively. Of the Staphylococcus aureus isolated 43 (71.7%) were methicillin resistant. The difference in the proportion of isolates that were MRSA observed in the two women groups is not statistically significantly (P>0.05). The MRSA isolates had 100%, 90.7% and 83.7% resistance to ampicillin, clindamycin and vancomycin respectively. They also showed 93-95% susceptibility to gentamicin, ciprofloxacin, ofloxacin, pefloxacin and sparfloxacin.
Conclusion: Methicillin resistant Staphylococcus aureus is highly prevalent in the urine of healthy women investigated in Federal Capital Territory. Their resistance to vancomycin, a glycopeptide that is rarely used in this environment calls for further investigations into the clinical significance of the observed resistance on the chemotherapy and outcomes of Staphylococcal infections. |
| first_indexed | 2024-04-12T07:45:29Z |
| format | Article |
| id | doaj.art-1bc4b322a81c4b25bcbc78932cc98587 |
| institution | Directory Open Access Journal |
| issn | 2635-3695 |
| language | English |
| last_indexed | 2024-04-12T07:45:29Z |
| publishDate | 2006-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Medicine and Health Development |
| spelling | doaj.art-1bc4b322a81c4b25bcbc78932cc985872022-12-22T03:41:43ZengWolters Kluwer Medknow PublicationsInternational Journal of Medicine and Health Development2635-36952006-01-011114752Prevalence of community-associated Methicillin-resistant Staphylococcus aureus (MRSA) isolates among women in Federal Capital Territory (Abuja), NigeriaAdebola OnanugaBusayo O OlayinkaAvosuahi R OyiJosiah A OnaolapoBackground: Community-associated methicillin-resistant Staphylococcus aureus is increasingly reported. This study investigated its prevalence in urine of healthy women and resistance pattern to other antibiotics. Methods: Urine samples collected from healthy women volunteers in Federal Capital Territory were cultured and screened for Staphylococcus aureus using standard microbiological procedures. The isolates were then subjected to antibiotic susceptibility testing using disc diffusion technique. Results: A total of 60 (40%) Staphylococcus aureus isolates were isolated from 150 urine samples collected. The prevalence rate from married and single women were 41% and 38% respectively. Of the Staphylococcus aureus isolated 43 (71.7%) were methicillin resistant. The difference in the proportion of isolates that were MRSA observed in the two women groups is not statistically significantly (P>0.05). The MRSA isolates had 100%, 90.7% and 83.7% resistance to ampicillin, clindamycin and vancomycin respectively. They also showed 93-95% susceptibility to gentamicin, ciprofloxacin, ofloxacin, pefloxacin and sparfloxacin. Conclusion: Methicillin resistant Staphylococcus aureus is highly prevalent in the urine of healthy women investigated in Federal Capital Territory. Their resistance to vancomycin, a glycopeptide that is rarely used in this environment calls for further investigations into the clinical significance of the observed resistance on the chemotherapy and outcomes of Staphylococcal infections.http://www.ijmhdev.com/article.asp?issn=2635-3695;year=2006;volume=11;issue=1;spage=47;epage=52;aulast=Onanuga;type=0prevalencemrsastaphylococcus aureuscommunity-associatedhealthy women |
| spellingShingle | Adebola Onanuga Busayo O Olayinka Avosuahi R Oyi Josiah A Onaolapo Prevalence of community-associated Methicillin-resistant Staphylococcus aureus (MRSA) isolates among women in Federal Capital Territory (Abuja), Nigeria International Journal of Medicine and Health Development prevalence mrsa staphylococcus aureus community-associated healthy women |
| title | Prevalence of community-associated Methicillin-resistant Staphylococcus aureus (MRSA) isolates among women in Federal Capital Territory (Abuja), Nigeria |
| title_full | Prevalence of community-associated Methicillin-resistant Staphylococcus aureus (MRSA) isolates among women in Federal Capital Territory (Abuja), Nigeria |
| title_fullStr | Prevalence of community-associated Methicillin-resistant Staphylococcus aureus (MRSA) isolates among women in Federal Capital Territory (Abuja), Nigeria |
| title_full_unstemmed | Prevalence of community-associated Methicillin-resistant Staphylococcus aureus (MRSA) isolates among women in Federal Capital Territory (Abuja), Nigeria |
| title_short | Prevalence of community-associated Methicillin-resistant Staphylococcus aureus (MRSA) isolates among women in Federal Capital Territory (Abuja), Nigeria |
| title_sort | prevalence of community associated methicillin resistant staphylococcus aureus mrsa isolates among women in federal capital territory abuja nigeria |
| topic | prevalence mrsa staphylococcus aureus community-associated healthy women |
| url | http://www.ijmhdev.com/article.asp?issn=2635-3695;year=2006;volume=11;issue=1;spage=47;epage=52;aulast=Onanuga;type=0 |
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