Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis Group
Over the last seven decades, applications using members of the Bacillus subtilis group have emerged in both food processes and crop protection industries. Their ability to form survival endospores and the plethora of antimicrobial compounds they produce has generated an increased industrial interest...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-02-01
|
| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fmicb.2019.00302/full |
| _version_ | 1828758373634408448 |
|---|---|
| author | Simon Caulier Simon Caulier Catherine Nannan Annika Gillis Florent Licciardi Claude Bragard Jacques Mahillon |
| author_facet | Simon Caulier Simon Caulier Catherine Nannan Annika Gillis Florent Licciardi Claude Bragard Jacques Mahillon |
| author_sort | Simon Caulier |
| collection | DOAJ |
| description | Over the last seven decades, applications using members of the Bacillus subtilis group have emerged in both food processes and crop protection industries. Their ability to form survival endospores and the plethora of antimicrobial compounds they produce has generated an increased industrial interest as food preservatives, therapeutic agents and biopesticides. In the growing context of food biopreservation and biological crop protection, this review suggests a comprehensive way to visualize the antimicrobial spectrum described within the B. subtilis group, including volatile compounds. This classification distinguishes the bioactive metabolites based on their biosynthetic pathways and chemical nature: i.e., ribosomal peptides (RPs), volatile compounds, polyketides (PKs), non-ribosomal peptides (NRPs), and hybrids between PKs and NRPs. For each clade, the chemical structure, biosynthesis and antimicrobial activity are described and exemplified. This review aims at constituting a convenient and updated classification of antimicrobial metabolites from the B. subtilis group, whose complex phylogeny is prone to further development. |
| first_indexed | 2024-12-11T00:41:46Z |
| format | Article |
| id | doaj.art-1bc5114222564768a7779f189a55793e |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-11T00:41:46Z |
| publishDate | 2019-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-1bc5114222564768a7779f189a55793e2022-12-22T01:26:54ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2019-02-011010.3389/fmicb.2019.00302435128Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis GroupSimon Caulier0Simon Caulier1Catherine Nannan2Annika Gillis3Florent Licciardi4Claude Bragard5Jacques Mahillon6Laboratory of Food and Environmental Microbiology, Earth and Life Institute, Université catholique de Louvain, Louvain-la-Neuve, BelgiumLaboratory of Phytopathology-Applied Microbiology, Earth and Life Institute, Université catholique de Louvain, Louvain-la-Neuve, BelgiumLaboratory of Food and Environmental Microbiology, Earth and Life Institute, Université catholique de Louvain, Louvain-la-Neuve, BelgiumLaboratory of Food and Environmental Microbiology, Earth and Life Institute, Université catholique de Louvain, Louvain-la-Neuve, BelgiumLaboratory of Food and Environmental Microbiology, Earth and Life Institute, Université catholique de Louvain, Louvain-la-Neuve, BelgiumLaboratory of Phytopathology-Applied Microbiology, Earth and Life Institute, Université catholique de Louvain, Louvain-la-Neuve, BelgiumLaboratory of Food and Environmental Microbiology, Earth and Life Institute, Université catholique de Louvain, Louvain-la-Neuve, BelgiumOver the last seven decades, applications using members of the Bacillus subtilis group have emerged in both food processes and crop protection industries. Their ability to form survival endospores and the plethora of antimicrobial compounds they produce has generated an increased industrial interest as food preservatives, therapeutic agents and biopesticides. In the growing context of food biopreservation and biological crop protection, this review suggests a comprehensive way to visualize the antimicrobial spectrum described within the B. subtilis group, including volatile compounds. This classification distinguishes the bioactive metabolites based on their biosynthetic pathways and chemical nature: i.e., ribosomal peptides (RPs), volatile compounds, polyketides (PKs), non-ribosomal peptides (NRPs), and hybrids between PKs and NRPs. For each clade, the chemical structure, biosynthesis and antimicrobial activity are described and exemplified. This review aims at constituting a convenient and updated classification of antimicrobial metabolites from the B. subtilis group, whose complex phylogeny is prone to further development.https://www.frontiersin.org/article/10.3389/fmicb.2019.00302/fullBacillus subtilis groupbacteriocinsbiocontrolbiosynthetic pathwayslipopeptidespolyketides |
| spellingShingle | Simon Caulier Simon Caulier Catherine Nannan Annika Gillis Florent Licciardi Claude Bragard Jacques Mahillon Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis Group Frontiers in Microbiology Bacillus subtilis group bacteriocins biocontrol biosynthetic pathways lipopeptides polyketides |
| title | Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis Group |
| title_full | Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis Group |
| title_fullStr | Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis Group |
| title_full_unstemmed | Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis Group |
| title_short | Overview of the Antimicrobial Compounds Produced by Members of the Bacillus subtilis Group |
| title_sort | overview of the antimicrobial compounds produced by members of the bacillus subtilis group |
| topic | Bacillus subtilis group bacteriocins biocontrol biosynthetic pathways lipopeptides polyketides |
| url | https://www.frontiersin.org/article/10.3389/fmicb.2019.00302/full |
| work_keys_str_mv | AT simoncaulier overviewoftheantimicrobialcompoundsproducedbymembersofthebacillussubtilisgroup AT simoncaulier overviewoftheantimicrobialcompoundsproducedbymembersofthebacillussubtilisgroup AT catherinenannan overviewoftheantimicrobialcompoundsproducedbymembersofthebacillussubtilisgroup AT annikagillis overviewoftheantimicrobialcompoundsproducedbymembersofthebacillussubtilisgroup AT florentlicciardi overviewoftheantimicrobialcompoundsproducedbymembersofthebacillussubtilisgroup AT claudebragard overviewoftheantimicrobialcompoundsproducedbymembersofthebacillussubtilisgroup AT jacquesmahillon overviewoftheantimicrobialcompoundsproducedbymembersofthebacillussubtilisgroup |