Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia
We aimed to analyze potential correlations between S-LANSS and PainDETECT with proxies for pain sensitization, e.g., the Central Sensitization Inventory (CSI) and pressure pain hyperalgesia (construct validity), pain-related or psychological variables (concurrent validity) in women with fibromyalgia...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/3/612 |
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| author | Edurne Úbeda-D’Ocasar Juan Antonio Valera-Calero Gracia María Gallego-Sendarrubias César Fernández-de-las-Peñas José Luis Arias-Buría Matilde Morales-Cabezas Lars Arendt-Nielsen Margarita Cigarán-Méndez |
| author_facet | Edurne Úbeda-D’Ocasar Juan Antonio Valera-Calero Gracia María Gallego-Sendarrubias César Fernández-de-las-Peñas José Luis Arias-Buría Matilde Morales-Cabezas Lars Arendt-Nielsen Margarita Cigarán-Méndez |
| author_sort | Edurne Úbeda-D’Ocasar |
| collection | DOAJ |
| description | We aimed to analyze potential correlations between S-LANSS and PainDETECT with proxies for pain sensitization, e.g., the Central Sensitization Inventory (CSI) and pressure pain hyperalgesia (construct validity), pain-related or psychological variables (concurrent validity) in women with fibromyalgia (FMS). One-hundred-and-twenty-six females with FMS completed demographic, pain-related variables, psychological, and sensitization outcomes as well as the S-LANSS and the PainDETECT questionnaires. S-LANSS was positively associated with BMI (r = 0.206), pain intensity (r = 0.206 to 0.298) and CSI score (r = 0.336) and negatively associated with all PPTs (r = −0.180 to −0.336). PainDETECT was negatively associated with age (r = −0.272) and all PPTs (r = −0.226 to −0.378) and positively correlated with pain intensity (r = 0.258 to 0.439), CSI (r = 0.538), anxiety (r = 0.246) and depression (r = 0.258). 51.4% of the S-LANSS was explained by PainDETECT (45.3%), posterior iliac PPT (0.2%) and mastoid PPT (5.9%), whereas the 56.4% of PainDETECT was explained by S-LANSS (43.4%), CSI (10.4%), and pain intensity (2.6%). This study found good convergent association between S-LANSS and PainDETECT in women with FMS. Additionally, S-LANSS was associated with PPTs whereas PainDETECT was associated with pain intensity and CSI, suggesting that both questionnaires assess different spectrums of the neuropathic and pain sensitization components of a condition and hence provide synergistic information. |
| first_indexed | 2024-03-09T20:05:32Z |
| format | Article |
| id | doaj.art-1bc53bd9c0ee438998f75c6afd2fa99f |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T20:05:32Z |
| publishDate | 2022-03-01 |
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| series | Biomedicines |
| spelling | doaj.art-1bc53bd9c0ee438998f75c6afd2fa99f2023-11-24T00:32:46ZengMDPI AGBiomedicines2227-90592022-03-0110361210.3390/biomedicines10030612Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with FibromyalgiaEdurne Úbeda-D’Ocasar0Juan Antonio Valera-Calero1Gracia María Gallego-Sendarrubias2César Fernández-de-las-Peñas3José Luis Arias-Buría4Matilde Morales-Cabezas5Lars Arendt-Nielsen6Margarita Cigarán-Méndez7Department of Physiotherapy, Faculty of Health, Universidad Camilo José Cela, 28692 Villanueva de la Cañada, SpainDepartment of Physiotherapy, Faculty of Health, Universidad Camilo José Cela, 28692 Villanueva de la Cañada, SpainDepartment of Physiotherapy, Faculty of Health, Universidad Camilo José Cela, 28692 Villanueva de la Cañada, SpainDepartment of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainDepartment of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainDepartment of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainCenter for Neuroplasticity and Pain (CNAP), Sanse-Motorisk Interaktion (SMI), Department of Health Science and Technology, Faculty of Medicine, Aalborg University, 9220 Aalborg, DenmarkDepartment of Psychology, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainWe aimed to analyze potential correlations between S-LANSS and PainDETECT with proxies for pain sensitization, e.g., the Central Sensitization Inventory (CSI) and pressure pain hyperalgesia (construct validity), pain-related or psychological variables (concurrent validity) in women with fibromyalgia (FMS). One-hundred-and-twenty-six females with FMS completed demographic, pain-related variables, psychological, and sensitization outcomes as well as the S-LANSS and the PainDETECT questionnaires. S-LANSS was positively associated with BMI (r = 0.206), pain intensity (r = 0.206 to 0.298) and CSI score (r = 0.336) and negatively associated with all PPTs (r = −0.180 to −0.336). PainDETECT was negatively associated with age (r = −0.272) and all PPTs (r = −0.226 to −0.378) and positively correlated with pain intensity (r = 0.258 to 0.439), CSI (r = 0.538), anxiety (r = 0.246) and depression (r = 0.258). 51.4% of the S-LANSS was explained by PainDETECT (45.3%), posterior iliac PPT (0.2%) and mastoid PPT (5.9%), whereas the 56.4% of PainDETECT was explained by S-LANSS (43.4%), CSI (10.4%), and pain intensity (2.6%). This study found good convergent association between S-LANSS and PainDETECT in women with FMS. Additionally, S-LANSS was associated with PPTs whereas PainDETECT was associated with pain intensity and CSI, suggesting that both questionnaires assess different spectrums of the neuropathic and pain sensitization components of a condition and hence provide synergistic information.https://www.mdpi.com/2227-9059/10/3/612fibromyalgianeuropathic painchronic painsensitizationpressure threshold |
| spellingShingle | Edurne Úbeda-D’Ocasar Juan Antonio Valera-Calero Gracia María Gallego-Sendarrubias César Fernández-de-las-Peñas José Luis Arias-Buría Matilde Morales-Cabezas Lars Arendt-Nielsen Margarita Cigarán-Méndez Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia Biomedicines fibromyalgia neuropathic pain chronic pain sensitization pressure threshold |
| title | Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia |
| title_full | Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia |
| title_fullStr | Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia |
| title_full_unstemmed | Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia |
| title_short | Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia |
| title_sort | association of neuropathic pain symptoms with sensitization related symptomatology in women with fibromyalgia |
| topic | fibromyalgia neuropathic pain chronic pain sensitization pressure threshold |
| url | https://www.mdpi.com/2227-9059/10/3/612 |
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