Analgesic effect of GT-0198, a structurally novel glycine transporter 2 inhibitor, in a mouse model of neuropathic pain

Analgesic effect of GT-0198, a structurally novel glycine transporter 2 inhibitor, in a mouse model of neuropathic pain

This study was conducted to identify the characteristic pharmacological features of GT-0198 that is phenoxymethylbenzamide derivatives. GT-0198 inhibited the function of glycine transporter 2 (GlyT2) in human GlyT2-expressing HEK293 cells and did not bind various major transporters or receptors of n...

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Bibliographic Details
Main Authors:	Yu Omori, Mayumi Nakajima, Kazumi Nishimura, Eiki Takahashi, Tadamasa Arai, Masato Akahira, Tomohiko Suzuki, Mie Kainoh
Format:	Article
Language:	English
Published:	Elsevier 2015-03-01
Series:	Journal of Pharmacological Sciences
Subjects:	Neuropathic pain Glycine Glycine transporter Partial sciatic nerve ligation
Online Access:	http://www.sciencedirect.com/science/article/pii/S134786131500050X

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