The Effects of Capparis Spinosa Leaves on The Histological Findings Associated With The Exposure of Mice to Trichloroacetic Acid
The present work was conducted to study the possible protective role of Capparis spinosa leaves and their efficacy against hematological and histological alterations resulted in an animal model intoxicated with trichloroacetis acid ( TCA). Hundred male mice 20-26 gm were divided into 5 groups ; con...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Alsalam university college
2022-01-01
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| Series: | Al-SalamJournal for Medical Science |
| Online Access: | http://journal.alsalam.edu.iq/index.php/ajbms/article/view/16 |
| _version_ | 1797450754217213952 |
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| author | Ghyath S. Mahmoud Raghed H. Rashed Afrah Jabbar Lazim Heyam Aziz Mohammed |
| author_facet | Ghyath S. Mahmoud Raghed H. Rashed Afrah Jabbar Lazim Heyam Aziz Mohammed |
| author_sort | Ghyath S. Mahmoud |
| collection | DOAJ |
| description |
The present work was conducted to study the possible protective role of Capparis spinosa leaves
and their efficacy against hematological and histological alterations resulted in an animal model intoxicated with
trichloroacetis acid ( TCA).
Hundred male mice 20-26 gm were divided into 5 groups ; control group , group II treated oraly with honey ( 40 mg /
Kg body weight for 3 weeks ) , group III treated orally with a mixture of Capparis spinosa leaves powder and honey (
40 mg/ Kg for 3 weeks) , group IV treated with TCA in drinking water ( 500 mg / Kg fpr 3 and 6 weeks , then left for
3 weeks for recovery) and group V ( Regeneration group ) treated with TCA for 6 weeks then treated with a mixture
of Capparis and honey ( 40 gm /Kg for 3 weeks).
Histological examination of spleen sections of mice treated with TCA revealed obvious pathological findings
including disorganization of lymphoid follicles , hyperplasia in white pulp , depletion of lymphocyts in red pulp
with subcapsular edema , some necrotic cells in white and red pulp , increasing megakarycoytes, haemosiderosis and
fibrosis in red pulp and in some lymphoid follocles. Administration of a mixture of Capparis spinosa leaves powder
and honey lessened most of the pathological lesions in mice intoxicated with TCA
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| first_indexed | 2024-03-09T14:44:11Z |
| format | Article |
| id | doaj.art-1bca5d95a39c4036b53b8863a7a6879d |
| institution | Directory Open Access Journal |
| issn | 2958-0870 2959-5398 |
| language | English |
| last_indexed | 2024-03-09T14:44:11Z |
| publishDate | 2022-01-01 |
| publisher | Alsalam university college |
| record_format | Article |
| series | Al-SalamJournal for Medical Science |
| spelling | doaj.art-1bca5d95a39c4036b53b8863a7a6879d2023-11-27T09:07:44ZengAlsalam university collegeAl-SalamJournal for Medical Science2958-08702959-53982022-01-011110.55145/ajbms.2022.1.1.00416The Effects of Capparis Spinosa Leaves on The Histological Findings Associated With The Exposure of Mice to Trichloroacetic AcidGhyath S. Mahmoud0Raghed H. Rashed1Afrah Jabbar Lazim2Heyam Aziz Mohammed3Medical Laboratory Technique Department AL Salam University CollegeMedical Laboratory Technique Department AL Salam University CollegeMedical Laboratory Technique Department AL Salam University CollegeMedical Laboratory Technique Department AL Salam University College The present work was conducted to study the possible protective role of Capparis spinosa leaves and their efficacy against hematological and histological alterations resulted in an animal model intoxicated with trichloroacetis acid ( TCA). Hundred male mice 20-26 gm were divided into 5 groups ; control group , group II treated oraly with honey ( 40 mg / Kg body weight for 3 weeks ) , group III treated orally with a mixture of Capparis spinosa leaves powder and honey ( 40 mg/ Kg for 3 weeks) , group IV treated with TCA in drinking water ( 500 mg / Kg fpr 3 and 6 weeks , then left for 3 weeks for recovery) and group V ( Regeneration group ) treated with TCA for 6 weeks then treated with a mixture of Capparis and honey ( 40 gm /Kg for 3 weeks). Histological examination of spleen sections of mice treated with TCA revealed obvious pathological findings including disorganization of lymphoid follicles , hyperplasia in white pulp , depletion of lymphocyts in red pulp with subcapsular edema , some necrotic cells in white and red pulp , increasing megakarycoytes, haemosiderosis and fibrosis in red pulp and in some lymphoid follocles. Administration of a mixture of Capparis spinosa leaves powder and honey lessened most of the pathological lesions in mice intoxicated with TCA http://journal.alsalam.edu.iq/index.php/ajbms/article/view/16 |
| spellingShingle | Ghyath S. Mahmoud Raghed H. Rashed Afrah Jabbar Lazim Heyam Aziz Mohammed The Effects of Capparis Spinosa Leaves on The Histological Findings Associated With The Exposure of Mice to Trichloroacetic Acid Al-SalamJournal for Medical Science |
| title | The Effects of Capparis Spinosa Leaves on The Histological Findings Associated With The Exposure of Mice to Trichloroacetic Acid |
| title_full | The Effects of Capparis Spinosa Leaves on The Histological Findings Associated With The Exposure of Mice to Trichloroacetic Acid |
| title_fullStr | The Effects of Capparis Spinosa Leaves on The Histological Findings Associated With The Exposure of Mice to Trichloroacetic Acid |
| title_full_unstemmed | The Effects of Capparis Spinosa Leaves on The Histological Findings Associated With The Exposure of Mice to Trichloroacetic Acid |
| title_short | The Effects of Capparis Spinosa Leaves on The Histological Findings Associated With The Exposure of Mice to Trichloroacetic Acid |
| title_sort | effects of capparis spinosa leaves on the histological findings associated with the exposure of mice to trichloroacetic acid |
| url | http://journal.alsalam.edu.iq/index.php/ajbms/article/view/16 |
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