State-of-All-the-Art and Prospective Hydrogel-Based Transdermal Drug Delivery Systems
Over the past few decades, notable advancements have been made in the field of transdermal drug delivery systems (TDDSs), presenting a promising alternative to conventional oral drug administration. This comprehensive review aims to enhance understanding of this method by examining various transderm...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/14/7/2926 |
| _version_ | 1797212823146725376 |
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| author | Meera Alex Nour M. Alsawaftah Ghaleb A. Husseini |
| author_facet | Meera Alex Nour M. Alsawaftah Ghaleb A. Husseini |
| author_sort | Meera Alex |
| collection | DOAJ |
| description | Over the past few decades, notable advancements have been made in the field of transdermal drug delivery systems (TDDSs), presenting a promising alternative to conventional oral drug administration. This comprehensive review aims to enhance understanding of this method by examining various transdermal techniques, the skin’s role as a barrier to TDDS, factors affecting skin diffusion, and current challenges in TDDSs. The primary focus of this analysis centers on TDDSs utilizing hydrogels. A thorough exploration of hydrogel fundamentals, encompassing structure, properties, and synthesis, is provided to underscore the importance of hydrogels as carriers in transdermal drug delivery. The concluding section delves into strategies for hydrogel-based drug delivery, addressing challenges and exploring future directions. |
| first_indexed | 2024-04-24T10:48:30Z |
| format | Article |
| id | doaj.art-1bcac93dfa1d48c388136435f92c9864 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-04-24T10:48:30Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-1bcac93dfa1d48c388136435f92c98642024-04-12T13:15:12ZengMDPI AGApplied Sciences2076-34172024-03-01147292610.3390/app14072926State-of-All-the-Art and Prospective Hydrogel-Based Transdermal Drug Delivery SystemsMeera Alex0Nour M. Alsawaftah1Ghaleb A. Husseini2Biosciences and Bioengineering PhD Program, American University of Sharjah, 26666 Sharjah, United Arab EmiratesMaterials Science and Engineering PhD Program, American University of Sharjah, 26666 Sharjah, United Arab EmiratesBiosciences and Bioengineering PhD Program, American University of Sharjah, 26666 Sharjah, United Arab EmiratesOver the past few decades, notable advancements have been made in the field of transdermal drug delivery systems (TDDSs), presenting a promising alternative to conventional oral drug administration. This comprehensive review aims to enhance understanding of this method by examining various transdermal techniques, the skin’s role as a barrier to TDDS, factors affecting skin diffusion, and current challenges in TDDSs. The primary focus of this analysis centers on TDDSs utilizing hydrogels. A thorough exploration of hydrogel fundamentals, encompassing structure, properties, and synthesis, is provided to underscore the importance of hydrogels as carriers in transdermal drug delivery. The concluding section delves into strategies for hydrogel-based drug delivery, addressing challenges and exploring future directions.https://www.mdpi.com/2076-3417/14/7/2926transdermal drug deliveryskinhydrogel |
| spellingShingle | Meera Alex Nour M. Alsawaftah Ghaleb A. Husseini State-of-All-the-Art and Prospective Hydrogel-Based Transdermal Drug Delivery Systems Applied Sciences transdermal drug delivery skin hydrogel |
| title | State-of-All-the-Art and Prospective Hydrogel-Based Transdermal Drug Delivery Systems |
| title_full | State-of-All-the-Art and Prospective Hydrogel-Based Transdermal Drug Delivery Systems |
| title_fullStr | State-of-All-the-Art and Prospective Hydrogel-Based Transdermal Drug Delivery Systems |
| title_full_unstemmed | State-of-All-the-Art and Prospective Hydrogel-Based Transdermal Drug Delivery Systems |
| title_short | State-of-All-the-Art and Prospective Hydrogel-Based Transdermal Drug Delivery Systems |
| title_sort | state of all the art and prospective hydrogel based transdermal drug delivery systems |
| topic | transdermal drug delivery skin hydrogel |
| url | https://www.mdpi.com/2076-3417/14/7/2926 |
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