Does a spontaneous cure for chagas' disease exist?
Six Costa Rican Chagas' disease patients, with wellknown acute phase history and no specific treatment were examined in several occasions during 39, 24, 32, 16 and 14 years, respectively, from the onset. Nome of the patients presented heart abnormalities as revealed by the conventional EKG and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
1988-03-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821988000100003&lng=en&tlng=en |
| _version_ | 1818554613961326592 |
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| author | Rodrigo Zeledón João Carlos P. Dias A. Brilla-Salazar J. Marcondes de Rezende Luis G. Vargas Andrea Urbina |
| author_facet | Rodrigo Zeledón João Carlos P. Dias A. Brilla-Salazar J. Marcondes de Rezende Luis G. Vargas Andrea Urbina |
| author_sort | Rodrigo Zeledón |
| collection | DOAJ |
| description | Six Costa Rican Chagas' disease patients, with wellknown acute phase history and no specific treatment were examined in several occasions during 39, 24, 32, 16 and 14 years, respectively, from the onset. Nome of the patients presented heart abnormalities as revealed by the conventional EKG and ergometry, exceptfor one of them with an incomplete block of the right bundle branch. Also, no alterations of the oesophagus motility was detected manometrically except for another patient who presented a slight hypersensivity reaction to a pharmacological test (Mecholyl). Three out of six patients became serologically negative in 1981, remaining as such until 1986. Besides the conventional serology, the search of protective ("lytic") antibodies was also performed in 1985 and 1986, being completely negative in one of the "cured" patients and dubious in the other two. The hypothesis that these three patients had as spontaneous cure, based on the clinical, serological and parasitologica l findings is discussed. |
| first_indexed | 2024-12-12T09:42:17Z |
| format | Article |
| id | doaj.art-1bcc75f082f04baf90cc00f951d49ba2 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-12-12T09:42:17Z |
| publishDate | 1988-03-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-1bcc75f082f04baf90cc00f951d49ba22022-12-22T00:28:32ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98491988-03-01211152010.1590/S0037-86821988000100003S0037-86821988000100003Does a spontaneous cure for chagas' disease exist?Rodrigo Zeledón0João Carlos P. Dias1A. Brilla-Salazar2J. Marcondes de Rezende3Luis G. Vargas4Andrea Urbina5Universidad Nacional de Costa RicaUniversidade Federal de Minas GeraisHospital MéxicoU.F.Universidad Nacional de Costa RicaUniversidad Nacional de Costa RicaSix Costa Rican Chagas' disease patients, with wellknown acute phase history and no specific treatment were examined in several occasions during 39, 24, 32, 16 and 14 years, respectively, from the onset. Nome of the patients presented heart abnormalities as revealed by the conventional EKG and ergometry, exceptfor one of them with an incomplete block of the right bundle branch. Also, no alterations of the oesophagus motility was detected manometrically except for another patient who presented a slight hypersensivity reaction to a pharmacological test (Mecholyl). Three out of six patients became serologically negative in 1981, remaining as such until 1986. Besides the conventional serology, the search of protective ("lytic") antibodies was also performed in 1985 and 1986, being completely negative in one of the "cured" patients and dubious in the other two. The hypothesis that these three patients had as spontaneous cure, based on the clinical, serological and parasitologica l findings is discussed.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821988000100003&lng=en&tlng=enTripanosomiase americanaDoença de ChagasCura espontâneaEstudo longitudinal |
| spellingShingle | Rodrigo Zeledón João Carlos P. Dias A. Brilla-Salazar J. Marcondes de Rezende Luis G. Vargas Andrea Urbina Does a spontaneous cure for chagas' disease exist? Revista da Sociedade Brasileira de Medicina Tropical Tripanosomiase americana Doença de Chagas Cura espontânea Estudo longitudinal |
| title | Does a spontaneous cure for chagas' disease exist? |
| title_full | Does a spontaneous cure for chagas' disease exist? |
| title_fullStr | Does a spontaneous cure for chagas' disease exist? |
| title_full_unstemmed | Does a spontaneous cure for chagas' disease exist? |
| title_short | Does a spontaneous cure for chagas' disease exist? |
| title_sort | does a spontaneous cure for chagas disease exist |
| topic | Tripanosomiase americana Doença de Chagas Cura espontânea Estudo longitudinal |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821988000100003&lng=en&tlng=en |
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