Investigation of aflatoxin M1 degradation in milk
Aflatoxin M1 is a highly toxic 4-hydroxylated metabolite of aflatoxins B1 and B2. It is one of the most potent hepatocarcinogens, mutagens, teratogens and immunosuppressors. Feed is often contaminated with aflatoxigenic moulds and aflatoxins with a high possibility of contaminating milk and...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Veterinary Medicine, Belgrade
2012-01-01
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| Series: | Veterinarski Glasnik |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0350-2457/2012/0350-24571206387S.pdf |
| Summary: | Aflatoxin M1 is a highly toxic 4-hydroxylated metabolite of aflatoxins B1 and
B2. It is one of the most potent hepatocarcinogens, mutagens, teratogens and
immunosuppressors. Feed is often contaminated with aflatoxigenic moulds and
aflatoxins with a high possibility of contaminating milk and dairy products
with aflatoxin M1. Samples of artificially contaminated milk were exposed to
the effects of physical conditions (temperature of -18oC and for microwaves
in a microwave oven), time (during the period from 1 to 12 months) and a
combination of the above mentioned conditions. Following this, levels of
aflatoxin M1 degradation were established by using the ELISA method. An
insignificant decrease in concentration of toxin was observed which indicates
that a temperature of -18°C does not significantly influence the
concentration of aflatoxin M1 in the artificially contaminated milk. At the
same time, treatment of milk with microwaves in a microwave oven showed an
insignificant influence on the percentage of aflatoxin M1 absorbance. |
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| ISSN: | 0350-2457 2406-0771 |