Comparison of Ultrasound Scores in Differentiating between Benign and Malignant Adnexal Masses
Subjective ultrasound assessment by an expert examiner is meant to be the best option for the differentiation between benign and malignant adnexal masses. Different ultrasound scores can help in the classification, but whether one of them is significantly better than others is still a matter of deba...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/7/1307 |
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| author | Mar Pelayo Irene Pelayo-Delgado Javier Sancho-Sauco Javier Sanchez-Zurdo Leopoldo Abarca-Martinez Virginia Corraliza-Galán Carmen Martin-Gromaz María Jesús Pablos-Antona Julia Zurita-Calvo Juan Luis Alcázar |
| author_facet | Mar Pelayo Irene Pelayo-Delgado Javier Sancho-Sauco Javier Sanchez-Zurdo Leopoldo Abarca-Martinez Virginia Corraliza-Galán Carmen Martin-Gromaz María Jesús Pablos-Antona Julia Zurita-Calvo Juan Luis Alcázar |
| author_sort | Mar Pelayo |
| collection | DOAJ |
| description | Subjective ultrasound assessment by an expert examiner is meant to be the best option for the differentiation between benign and malignant adnexal masses. Different ultrasound scores can help in the classification, but whether one of them is significantly better than others is still a matter of debate. The main aim of this work is to compare the diagnostic performance of some of these scores in the evaluation of adnexal masses in the same set of patients. This is a retrospective study of a consecutive series of women diagnosed as having a persistent adnexal mass and managed surgically. Ultrasound characteristics were analyzed according to IOTA criteria. Masses were classified according to the subjective impression of the sonographer and other ultrasound scores (IOTA simple rules -SR-, IOTA simple rules risk assessment -SRRA-, O-RADS classification, and ADNEX model -with and without CA125 value-). A total of 122 women were included. Sixty-two women were postmenopausal (50.8%). Eighty-one women had a benign mass (66.4%), and 41 (33.6%) had a malignant tumor. The sensitivity of subjective assessment, IOTA SR, IOTA SRRA, and ADNEX model with or without CA125 and O-RADS was 87.8%, 66.7%, 78.1%, 95.1%, 87.8%, and 90.2%, respectively. The specificity for these approaches was 69.1%, 89.2%, 72.8%, 74.1%, 67.9%, and 60.5%, respectively. All methods with similar AUC (0.81, 0.78, 0.80, 0.88, 0.84, and 0.75, respectively). We concluded that IOTA SR, IOTA SRRA, and ADNEX models with or without CA125 and O-RADS can help in the differentiation of benign and malignant masses, and their performance is similar to the subjective assessment of an experienced sonographer. |
| first_indexed | 2024-03-11T05:39:33Z |
| format | Article |
| id | doaj.art-1bd06bf0ca4e4e5193cd3ee289de5d2d |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T05:39:33Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-1bd06bf0ca4e4e5193cd3ee289de5d2d2023-11-17T16:30:45ZengMDPI AGDiagnostics2075-44182023-03-01137130710.3390/diagnostics13071307Comparison of Ultrasound Scores in Differentiating between Benign and Malignant Adnexal MassesMar Pelayo0Irene Pelayo-Delgado1Javier Sancho-Sauco2Javier Sanchez-Zurdo3Leopoldo Abarca-Martinez4Virginia Corraliza-Galán5Carmen Martin-Gromaz6María Jesús Pablos-Antona7Julia Zurita-Calvo8Juan Luis Alcázar9Department of Radiology, Hospital HM Puerta del Sur, 28938 Móstoles, SpainDepartment of Obstetrics and Gynecology, Hospital Ramon y Cajal, 28034 Madrid, SpainDepartment of Obstetrics and Gynecology, Hospital Ramon y Cajal, 28034 Madrid, SpainInsight Technology Solutions, 28108 Madrid, SpainDepartment of Obstetrics and Gynecology, Hospital Ramon y Cajal, 28034 Madrid, SpainDepartment of Obstetrics and Gynecology, Hospital Ramon y Cajal, 28034 Madrid, SpainDepartment of Obstetrics and Gynecology, Hospital Ramon y Cajal, 28034 Madrid, SpainDepartment of Obstetrics and Gynecology, Hospital Ramon y Cajal, 28034 Madrid, SpainDepartment of Obstetrics and Gynecology, Hospital Ramon y Cajal, 28034 Madrid, SpainDepartment of Obstetrics and Gynecology, Clinica Universidad de Navarra, 31008 Pamplona, SpainSubjective ultrasound assessment by an expert examiner is meant to be the best option for the differentiation between benign and malignant adnexal masses. Different ultrasound scores can help in the classification, but whether one of them is significantly better than others is still a matter of debate. The main aim of this work is to compare the diagnostic performance of some of these scores in the evaluation of adnexal masses in the same set of patients. This is a retrospective study of a consecutive series of women diagnosed as having a persistent adnexal mass and managed surgically. Ultrasound characteristics were analyzed according to IOTA criteria. Masses were classified according to the subjective impression of the sonographer and other ultrasound scores (IOTA simple rules -SR-, IOTA simple rules risk assessment -SRRA-, O-RADS classification, and ADNEX model -with and without CA125 value-). A total of 122 women were included. Sixty-two women were postmenopausal (50.8%). Eighty-one women had a benign mass (66.4%), and 41 (33.6%) had a malignant tumor. The sensitivity of subjective assessment, IOTA SR, IOTA SRRA, and ADNEX model with or without CA125 and O-RADS was 87.8%, 66.7%, 78.1%, 95.1%, 87.8%, and 90.2%, respectively. The specificity for these approaches was 69.1%, 89.2%, 72.8%, 74.1%, 67.9%, and 60.5%, respectively. All methods with similar AUC (0.81, 0.78, 0.80, 0.88, 0.84, and 0.75, respectively). We concluded that IOTA SR, IOTA SRRA, and ADNEX models with or without CA125 and O-RADS can help in the differentiation of benign and malignant masses, and their performance is similar to the subjective assessment of an experienced sonographer.https://www.mdpi.com/2075-4418/13/7/1307transvaginal ultrasoundadnexal massesIOTA simple rulesIOTA simple rules risk assessmentO-RADSADNEX model |
| spellingShingle | Mar Pelayo Irene Pelayo-Delgado Javier Sancho-Sauco Javier Sanchez-Zurdo Leopoldo Abarca-Martinez Virginia Corraliza-Galán Carmen Martin-Gromaz María Jesús Pablos-Antona Julia Zurita-Calvo Juan Luis Alcázar Comparison of Ultrasound Scores in Differentiating between Benign and Malignant Adnexal Masses Diagnostics transvaginal ultrasound adnexal masses IOTA simple rules IOTA simple rules risk assessment O-RADS ADNEX model |
| title | Comparison of Ultrasound Scores in Differentiating between Benign and Malignant Adnexal Masses |
| title_full | Comparison of Ultrasound Scores in Differentiating between Benign and Malignant Adnexal Masses |
| title_fullStr | Comparison of Ultrasound Scores in Differentiating between Benign and Malignant Adnexal Masses |
| title_full_unstemmed | Comparison of Ultrasound Scores in Differentiating between Benign and Malignant Adnexal Masses |
| title_short | Comparison of Ultrasound Scores in Differentiating between Benign and Malignant Adnexal Masses |
| title_sort | comparison of ultrasound scores in differentiating between benign and malignant adnexal masses |
| topic | transvaginal ultrasound adnexal masses IOTA simple rules IOTA simple rules risk assessment O-RADS ADNEX model |
| url | https://www.mdpi.com/2075-4418/13/7/1307 |
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