The Warburg Effect in Endothelial Cells and its Potential as an Anti-angiogenic Target in Cancer

The Warburg Effect in Endothelial Cells and its Potential as an Anti-angiogenic Target in Cancer

Endothelial cells (ECs) make up the lining of our blood vessels and they ensure optimal nutrient and oxygen delivery to the parenchymal tissue. In response to oxygen and/or nutrient deprivation, ECs become activated and sprout into hypo-vascularized tissues forming new vascular networks in a process...

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Bibliographic Details
Main Authors: Gillian Fitzgerald, Inés Soro-Arnaiz, Katrien De Bock
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
angiogenesis
endothelial
metabolism
cancer
vascular normalization
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00100/full

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