Effects of Fermented Sumach on the Formation of Slime Layer of Staphylococcus aureus
Objective: Staphylococcus aureus (S. aureus) is one of the most commonly isolated bacterial pathogens in hospitals, and the most frequent cause of nosocomial infections. Nosocomial staphylococcal foreign-body infections related to biofilm formation are a serious threat, demanding new therapeutic and...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2012-03-01
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| Series: | Balkan Medical Journal |
| Subjects: | |
| Online Access: | http://www.tutfd.org/text.php3?id=835 |
| _version_ | 1797923736290066432 |
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| author | Sahra Kırmusaoğlu Seyhun Yurdugül Esra Koçoğlu |
| author_facet | Sahra Kırmusaoğlu Seyhun Yurdugül Esra Koçoğlu |
| author_sort | Sahra Kırmusaoğlu |
| collection | DOAJ |
| description | Objective: Staphylococcus aureus (S. aureus) is one of the most commonly isolated bacterial pathogens in hospitals, and the most frequent cause of nosocomial infections. Nosocomial staphylococcal foreign-body infections related to biofilm formation are a serious threat, demanding new therapeutic and preventive strategies. Implantation of intravenous catheters and surgical implantation of prosthetic implants carry a risk of infection. In order to prevent all these effects of biofilms, a study was designed to observe the possible antibacterial effect of sumach (Rhus coriaria) on the biofilm formation of S. aureus. Material and Methods: The influence of varying concentrations of sumach on the formation of biofilms by 13 strains of Staphylococcus aureus was tested by a microelisa assay. Results: The significant differences between varying concentrations of sumach (0.1, 0.2, 0.5 and 1.0 µl/ml) were observed in four methicillin resistant Staphylococcus aureus (MRSA) and nine methicillin sensitive Staphylococcus aureus (MSSA) (p<0.05). In bacteria, a dose-related decrease in the formation of slime, which is a major virulence factor of staphylococcal infections, was observed. Conclusion: In our study, using 0.1, 0.2, 0.5 and 1.0 µl/ml of sumach, thirteen strains lost, 17%, 22%, 28% and 48% respectively of their capacity to produce biofilms. Sumach, which is a herbal product, can decrease the formation of biofilm, which is a major virulence factor in staphylococcal infections. |
| first_indexed | 2024-04-10T14:50:53Z |
| format | Article |
| id | doaj.art-1bd1e3e8dba64f34be9317e4e753a0ea |
| institution | Directory Open Access Journal |
| issn | 2146-3123 2146-3131 |
| language | English |
| last_indexed | 2024-04-10T14:50:53Z |
| publishDate | 2012-03-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Balkan Medical Journal |
| spelling | doaj.art-1bd1e3e8dba64f34be9317e4e753a0ea2023-02-15T16:07:35ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312012-03-012918487Effects of Fermented Sumach on the Formation of Slime Layer of Staphylococcus aureusSahra KırmusaoğluSeyhun YurdugülEsra KoçoğluObjective: Staphylococcus aureus (S. aureus) is one of the most commonly isolated bacterial pathogens in hospitals, and the most frequent cause of nosocomial infections. Nosocomial staphylococcal foreign-body infections related to biofilm formation are a serious threat, demanding new therapeutic and preventive strategies. Implantation of intravenous catheters and surgical implantation of prosthetic implants carry a risk of infection. In order to prevent all these effects of biofilms, a study was designed to observe the possible antibacterial effect of sumach (Rhus coriaria) on the biofilm formation of S. aureus. Material and Methods: The influence of varying concentrations of sumach on the formation of biofilms by 13 strains of Staphylococcus aureus was tested by a microelisa assay. Results: The significant differences between varying concentrations of sumach (0.1, 0.2, 0.5 and 1.0 µl/ml) were observed in four methicillin resistant Staphylococcus aureus (MRSA) and nine methicillin sensitive Staphylococcus aureus (MSSA) (p<0.05). In bacteria, a dose-related decrease in the formation of slime, which is a major virulence factor of staphylococcal infections, was observed. Conclusion: In our study, using 0.1, 0.2, 0.5 and 1.0 µl/ml of sumach, thirteen strains lost, 17%, 22%, 28% and 48% respectively of their capacity to produce biofilms. Sumach, which is a herbal product, can decrease the formation of biofilm, which is a major virulence factor in staphylococcal infections.http://www.tutfd.org/text.php3?id=835Staphylococcus aureusbiofilm formationRhus coriariaIndwelling device-associated infections |
| spellingShingle | Sahra Kırmusaoğlu Seyhun Yurdugül Esra Koçoğlu Effects of Fermented Sumach on the Formation of Slime Layer of Staphylococcus aureus Balkan Medical Journal Staphylococcus aureus biofilm formation Rhus coriaria Indwelling device-associated infections |
| title | Effects of Fermented Sumach on the Formation of Slime Layer of Staphylococcus aureus |
| title_full | Effects of Fermented Sumach on the Formation of Slime Layer of Staphylococcus aureus |
| title_fullStr | Effects of Fermented Sumach on the Formation of Slime Layer of Staphylococcus aureus |
| title_full_unstemmed | Effects of Fermented Sumach on the Formation of Slime Layer of Staphylococcus aureus |
| title_short | Effects of Fermented Sumach on the Formation of Slime Layer of Staphylococcus aureus |
| title_sort | effects of fermented sumach on the formation of slime layer of staphylococcus aureus |
| topic | Staphylococcus aureus biofilm formation Rhus coriaria Indwelling device-associated infections |
| url | http://www.tutfd.org/text.php3?id=835 |
| work_keys_str_mv | AT sahrakırmusaoglu effectsoffermentedsumachontheformationofslimelayerofstaphylococcusaureus AT seyhunyurdugul effectsoffermentedsumachontheformationofslimelayerofstaphylococcusaureus AT esrakocoglu effectsoffermentedsumachontheformationofslimelayerofstaphylococcusaureus |