The relationship between protein modified folding molecular network and Alzheimer’s disease pathogenesis based on BAG2-HSC70-STUB1-MAPT expression patterns analysis

The relationship between protein modified folding molecular network and Alzheimer’s disease pathogenesis based on BAG2-HSC70-STUB1-MAPT expression patterns analysis

BackgroundAlzheimer’s disease (AD) is the most common cause of dementia and cognitive decline, while its pathological mechanism remains unclear. Tauopathies is one of the most widely accepted hypotheses. In this study, the molecular network was established and the expression pattern of the core gene...

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Bibliographic Details
Main Authors: Xiaolong Yang, Wenbo Guo, Lin Yang, Xuehui Li, Zhengkun Zhang, Xinping Pang, Ji Liu, Chaoyang Pang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer disease
gene expression level
tau
BAG2
HSC70
STUB1
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1090400/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1090400/full

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