Nanocomposites Based on PCL and Halloysite Nanotubes Filled with Lysozyme: Effect of Draw Ratio on the Physical Properties and Release Analysis

Halloysite nanotubes (HNTs) were loaded with lsozyme, as antimicrobial molecule, at a HNTs/lysozyme ratio of 1:1. Such a nano-hybrid was incorporated into a poly (ε-caprolactone) (PCL) matrix at 10 wt % and films were obtained. The nano-composites were submitted to a cold drawn process at three diff...

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Bibliographic Details
Main Authors: Valeria Bugatti, Gianluca Viscusi, Carlo Naddeo, Giuliana Gorrasi
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/7/8/213
Description
Summary:Halloysite nanotubes (HNTs) were loaded with lsozyme, as antimicrobial molecule, at a HNTs/lysozyme ratio of 1:1. Such a nano-hybrid was incorporated into a poly (ε-caprolactone) (PCL) matrix at 10 wt % and films were obtained. The nano-composites were submitted to a cold drawn process at three different draw ratios, λ = 3, 4, and 5, where λ is l(final length)/l0(initial length). Morphology, physical, and barrier properties of the starting nanocomposite and drawn samples were studied, and correlated to the release of the lysozyme molecule. It was demonstrated that with a simple mechanical treatment it is possible to obtain controlled release systems for specific active packaging requirements.
ISSN:2079-4991